# MassaChusetts General Hospital ROybal CeNter For BehavIoral Dyadic ResEarch in Alzheimer's Disease and Related Dementias (CONFIDE-ADRD): Administrative Component

> **NIH NIH P30** · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $448,223

## Abstract

PROJECT SUMMARY (ADMINISTRATIVE CORE):
The mission of the “MassaChusetts General Hospital ROybal CeNter For BehavIoral Dyadic ResEarch in Alzheimer’s
Disease and Related Dementias” (CONFIDE-ADRD) is the development, optimization, testing and implementation of
dyadic behavioral prevention interventions (DBPIs) across the spectrum of ADRD in both hospital and community settings,
to improve health and prevent negative individual and dyadic health outcomes. The Administrative Core (AC) will
contribute to this mission by guiding the overall direction of CONFIDE-ADRD and serving as a central communication and
decision-making hub. The AC will support the CONFIDE-ADRD mission in 3 main ways: 1) organize and guide the center’s
overall direction and ensure proper allocation of resources through overseeing the integration with the Behavioral
Intervention Development Core, MGH (NIA funded AD/ADRD RCMAR, NIA funded R25 dementia palliative care, NIA
funded T32 in behavioral interventions in aging, Mongan Institute, ADRC, Research Institute, Harvard Catalyst, etc) and
national (IMPACT Collaboratory, Pepper Centers, Roybal Coordinating Center, other Roybals, RCMAR coordinating
center) resources, as well as our Advisory Committee; 2) leverage the CONFIDE-ADRD resources and expertise at all
levels of the NIH Stage model including other components of our conceptual model (Science of Behavior Change, NIA
Health Disparities Framework, Center for Disease Control Prevention model and dyadic theory and interpersonal processes)
to integrate and structure local and national resources and foster experiential learning of research skills necessary to develop,
test and implement rigorous dementia DBPIs and swiftly translate them across the NIH stage model and into routine care,
and foster interdisciplinary collaborations across investigators; and 3) evaluate and monitor the process and outcome
indicators of funded pilot projects and CONFIDE-ADRD activities. Specific aims of the AC are: 1) Coordinate and oversee
the administrative functions of CONFIDE-ADRD in order to establish and maintain centralized research resources and a
stable research infrastructure to advance dementia DBPI research across the spectrum of ADRD, to improve health and
prevent negative health outcomes across hospital and community settings; 2) Optimize the use of all CONFIDE-ADRD
center resources and expertise in elements of our conceptual model, to facilitate, monitor, and accelerate pilot research and
provide an enriched interdisciplinary environment; and 3) Evaluate funded pilot projects and CONFIDE-ADRD activities,
make subsequent refinements, and report annually on the overall effectiveness and efficiency of our Center, its cores, and
funded pilot projects. Our Center includes evidence-based method for teaching from Bandura’s Social Cognitive Theory as
well as a novel method of evaluation that includes the NIH stage model and elements of our conceptual model. The MPI
and investigators have rich exper...

## Key facts

- **NIH application ID:** 10874323
- **Project number:** 1P30AG086562-01
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **Principal Investigator:** Ana-Maria Vranceanu
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $448,223
- **Award type:** 1
- **Project period:** 2024-08-15 → 2026-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10874323

## Citation

> US National Institutes of Health, RePORTER application 10874323, MassaChusetts General Hospital ROybal CeNter For BehavIoral Dyadic ResEarch in Alzheimer's Disease and Related Dementias (CONFIDE-ADRD): Administrative Component (1P30AG086562-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10874323. Licensed CC0.

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