# Reinvigorating HIV Prevention and Care for People Who Use Drugs: Accelerating Progress and Sustaining Gains in the Midst of Societal Disruption

> **NIH NIH P30** · NEW YORK UNIVERSITY · 2024 · $400,778

## Abstract

Project Summary/Abstract – Transdisciplinary Research Methods Core
The overarching goals of the Transdisciplinary Research Methods (TRM) Core are to (1) train and support our
affiliated investigators in application of relevant research methods, including methods that may be new or
complex, (2) make our investigators aware of innovative, cutting-edge methods that may be useful in their work
and can open up possibilities that inspire new research questions, and (3) contribute to methodological
advances. One primary area of emphasis will be on methods needed to understand the impacts of multilevel,
time-varying processes and Big Events/BigTrends (BE/BT) on HIV prevention and care among PWUD. To
support the work of a multidisciplinary set of investigators, we represent a range of expertise that includes field
research and sampling; ethnography; infectious disease etiology, epidemiology and surveillance; community-
engaged research; intervention design and testing, including optimization; and (now) designs and methods for
causal inference, and the frameworks and methods of implementation science. This expertise is needed to
understand how BE/BT impact the lives and health of PWUD, and to carry out research to develop
interventions that will be relevant, resilient, and adaptable to societal changes. Building on prior successes, this
Core will continue to focus on assisting affiliated investigators to integrate study design and methods with
theories of prevention and care; create testable models of causal pathways; detect and respond to HIV
outbreaks and other sequelae of BE/BT; and develop, test and implement potent and sustainable social,
behavioral, and social-structural interventions. Specific Aims of the TRM core are: Aim 1. Lead the field and
support CDUHR affiliated investigators in applying methods to enhance research conducted in the context of
disruptions due to BE/BT by providing training, seminars, and consultation on quantitative, qualitative, and
mixed methods, including the creative application and novel extensions of existing methods. Aim 2. Lead the
field in the integration of the multiphase optimization strategy (MOST), implementation science (IS), and
community-based participatory research (CBPR) methods, and build the capacity of CDUHR investigators to
develop highly effective, efficient, implementable, and sustainable behavioral, biobehavioral, and social-
structural interventions for prevention and treatment of HIV among PWUD by providing training and support in
this area. Aim 3. Disseminate new research methods to the larger field, particularly methods relevant to
responding to societal changes which may undermine or facilitate effective HIV prevention and care among
PWUD.

## Key facts

- **NIH application ID:** 10874380
- **Project number:** 5P30DA011041-27
- **Recipient organization:** NEW YORK UNIVERSITY
- **Principal Investigator:** LINDA M COLLINS
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $400,778
- **Award type:** 5
- **Project period:** 1998-04-01 → 2028-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10874380

## Citation

> US National Institutes of Health, RePORTER application 10874380, Reinvigorating HIV Prevention and Care for People Who Use Drugs: Accelerating Progress and Sustaining Gains in the Midst of Societal Disruption (5P30DA011041-27). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10874380. Licensed CC0.

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