# Pilot Projects Program

> **NIH NIH P30** · RHODE ISLAND HOSPITAL · 2024 · $195,186

## Abstract

PROGRAM SUMMARY/ABSTRACT - STEM CELL AND AGING COBRE PILOT GRANT PROGRAM
Building on the success of our Phase 1 and 2 COBRE program, we propose the Stem Cells and Aging (SCA)
COBRE Pilot Grants Program with an objective to recruit promising teams of early-stage investigators by
providing a funding mechanism for pilot projects and provide intellectual, technical and instrumental
infrastructure. In Specific Aim 1, we will select teams of translational researchers (consisting of basic and clinical
scientists, with at least one early-stage investigator) for 3 pilot project awards ($50,000 per year for 2 years and
minimum of 6 awards for the duration of the program), with additional summer stipends for students from under-
represented groups to enhance diversity. The request for proposals will focus on projects with high potential of
translating basic research into clinical practice. In Specific Aim 2, we will provide structured, formal mentorship
(provided by senior, extramurally-funded investigators) for participating early-stage basic- and clinician-scientist
investigators focused on stem cell and aging research, regenerative medicine and age-related diseases to
facilitate their transition to research independence with extramural funding. In Specific Aim 3, we will promote
the utilization and sustainability of the SCA COBRE Core Facilities (developed in Phases 1 and 2, and including
Flow Cytometry, Extracellular Vesicles, Lentiviral Construct Core Facilities) through their utilization in the pilot
projects as well as through vouchers to affiliated scientists participating in the program. In the Specific Aim 4, we
will provide post-award mentorship, advisory and grantsmanship services for program awardees, and synergize
efforts to transform funded projects into competitive applications at the R01 or equivalent level. Emphasis will be
placed on rigorous, reproducible science with analysis supported by expert biostatisticians guiding the
participating researchers. The core of the program will rely on the work of the SCA Pilot Grants Program Steering
Committee who will provide mentoring and oversight and engage (for identification of early-stage investigators,
for review of the pilot awards, and expert mentorship) the community of researchers across the multi-institutional
consortium encompassing Brow University (Center of the Biology of Aging, Brown and Lifespan Cancer Centers),
the Warren Alpert Medical School, the clinical experts from the Lifespan healthcare/Rhode Island Hospital and
from Care new England. By establishing a multidisciplinary scientific infrastructure providing access to state-of-
the-art instrumentation and technologies, as well as rigorous mentorship, advising, review and outcome
guidance, the Phase 3 SCA COBRE Pilot Grant Program will contribute to expansion and transformation the
biomedical and educational landscape within Rhode Island, creating a premier national center for research on
stem cell, aging, and regenerative medicin...

## Key facts

- **NIH application ID:** 10874453
- **Project number:** 5P30GM145500-02
- **Recipient organization:** RHODE ISLAND HOSPITAL
- **Principal Investigator:** Patrycja Marta Dubielecka-Szczerba
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $195,186
- **Award type:** 5
- **Project period:** 2023-07-01 → 2028-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10874453

## Citation

> US National Institutes of Health, RePORTER application 10874453, Pilot Projects Program (5P30GM145500-02). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10874453. Licensed CC0.

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*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
