# The impact of COVID-19 pandemic-related stressors on childhood obesity and cardiometabolic risk

> **NIH NIH R01** · UNIVERSITY OF MINNESOTA · 2024 · $643,287

## Abstract

Project Summary/Abstract
The COVID-19 pandemic has had an alarming impact on already unacceptably high childhood obesity rates,
and emerging evidence shows that traditional approaches to pediatric weight management have been
markedly less effective since the onset of the pandemic. As obesity during childhood is much more likely to be
sustained during adulthood, and children with obesity and other chronic conditions are more likely to have
severe forms of COVID-19 requiring hospitalization, this alarming increase in childhood obesity rates is poised
to have a broad and long-term impact on population health unless effective interventions are implemented. Yet,
we know very little about the unique drivers of this dramatic increase in childhood obesity and whether BMI
increases will persist and become lifelong. We know even less about the protective factors that mitigate this
risk, as some youth will not develop obesity/worsening cardiometabolic health or may recover quickly despite
risk exposures. Our goals are to uncover the biobehavioral pathways through which pandemic-related
stressors drive childhood obesity and cardiometabolic risk, and to identify protective factors and intervention
targets to mitigate the long-term impact of the pandemic on children’s health. The proposed research offers a
unique, time-sensitive opportunity to prospectively examine the impact of multilevel stressors brought on by the
pandemic to identify factors influencing BMI and cardiometabolic health trajectories. We will leverage an
established longitudinal cohort of racially/ethnically diverse children (60% Latino) from predominantly low-
income households, who were enrolled at 2-4 years of age (U01HD068890) and followed annually through
ages 7-11 (R01HD090059). Underscoring the timeliness, uniqueness, and significance of this cohort, body
composition, cardiovascular and metabolic functioning, neuroendocrine, oxidative stress, and inflammatory
biomarkers, and health behaviors were obtained just prior to the onset of the pandemic (n=338). Drawing on a
rich history of longitudinal data over 5 previous timepoints including immediately prior to the pandemic, we
propose to add two new waves of data collection (7- and 8-years after inception of the cohort, 2-3 years post-
onset of the pandemic) when children will be 10-14 years of age, an important developmental window of
obesity and cardiometabolic imprinting. Multiple levels of pandemic-related stressors will be measured,
alongside gold standard biological measures of stress activation, adiposity and cardiometabolic health,
objective health behavior measures, and parent-child surveys. Our specific aims focus on identifying the
pathways, parent-child factors, and neighborhood/community contexts needed to guide effective childhood
obesity interventions in the aftermath of the pandemic and reduce adverse health consequences among
vulnerable and understudied populations.

## Key facts

- **NIH application ID:** 10877955
- **Project number:** 5R01DK131410-03
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** Alicia S Kunin-Batson
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $643,287
- **Award type:** 5
- **Project period:** 2022-09-19 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10877955

## Citation

> US National Institutes of Health, RePORTER application 10877955, The impact of COVID-19 pandemic-related stressors on childhood obesity and cardiometabolic risk (5R01DK131410-03). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10877955. Licensed CC0.

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