PROJECT ABSTRACT This application presents the Integrated Networks of Scholars in Global Health Research Training (INSIGHT) Program. We have 145 faculty members across our multidisciplinary and multi-institutional consortium working together with 24 low- and middle-income countries (LMIC) institutions in sub-Saharan Africa, South Asia, and the Latin America and the Caribbean. A strategic planning process; including a comprehensive review of our consortium's role in combatting the global HIV epidemic, emerging and reemerging infectious diseases, non- communicable diseases, and mental health; was conducted to inform this proposal. A vision statement encompassing five Themes – Global Impact, Multidisciplinary Science, Integrated Training with Equal Partnership, Diverse Generation of Global Health Researchers, and Highly Committed Environment– shapes our work. Key innovations strengthening this proposal include ensuring diversity at the leadership level and across all research areas; leveraging our institutional commitments in global research training; amalgamating our strong foundations in clinical, behavioral and laboratory science; enacting a participatory monitoring and evaluation program; and launching emerging leaders. Aim 1 – Create collaborative, interdisciplinary global health research that integrates cross-institutional pairing of mentors. The research training “triad” of US mentor, LMIC mentor, and scholar form a long-term training partnership that builds research capacity of the scholars and the LMIC partner institutions. Outcomes: Robust interdisciplinary collaboration engendering innovative research driven by integration and equal partnership between our four universities and LMIC partners. Aim 2 – Provide one-year research training for 105 scholars with linkage to the Mentorship Triad Paradigm. We will provide training for five yearly cohorts of 15 scholars (9 US post- docs, 2 US pre-docs, and 4 LMIC post-docs) in global health research, including coursework and a mentored research practicum. We will leverage institutional commitment of $1.5 million to support an additional 30 scholars over five years to maximize impact. Outcomes: 90% of scholars completing training will submit grant proposals and/or publish their research. Aim 3 – Promote and support diversity, equity and inclusion in global health research training. We will leverage our existing initiatives and affiliations with Minority Serving Institutions and pipeline programs. This will include broad outreach to departments, centers, and schools at partner universities; and engaging student groups and associations of underrepresented populations in global health. Outcomes: 50% of LMIC scholars will be women and at least 30% of US scholars will be from underrepresented minorities. Aim 4 – Support the transition of scholars into successful and sustainable research careers. We will link scholar selection to LMIC priorities and research programs. Outcomes: Sustained collaboration bet...