This renewal application requests continued funding for years 31-35 of a successful, longstanding program for predoctoral training in Immunology and Pathogenesis. Four predoctoral positions are requested. Trainees are typically supported for 2 years, allowing for approximately 12 trainees. The goal of the training program is to prepare trainees for productive careers in academia, industry, or other science-related occupations. The Training Faculty are experienced researchers drawn from multiple departments across the Institution including Microbiology and Immunology, Biology, Biochemistry, Pathology, Surgery, and Regenerative Medicine. The Training Faculty possess a broad array of expertise while sharing a strong focus on immunology and pathogenesis. This T32 Program in Immunology and Pathogenesis has clear strengths that enhance predoctoral training, including: 1) innovative mechanisms such as the Career Development Workshops, Chalk Talks, Training in Communicating Science to the Public, and Opportunities for Community Engagement which enhance and add value to graduate training above that which is normally found in a graduate program, 2) a diverse training faculty which draws from a number of research programs throughout the Institution, and 3) a history of success in the recruitment of URM students. The success of the Training Program is evidenced by a very strong publication record and multiple meeting presentations by the Trainees. Finally, students move on to high quality postdoctoral and career positions following their training.