# Administrative and Biostatistics Core

> **NIH NIH P01** · SALK INSTITUTE FOR BIOLOGICAL STUDIES · 2024 · $195,148

## Abstract

PROJECT SUMMARY – Administrative and Biostatistics Core
The overall goal of the Administrative and Biostatistics Core (Admin Core) is to facilitate research efforts toward
understanding intrinsic resistance to therapy in pancreatic ductal adenocarcinoma (PDA). This will be
accomplished by providing the three Research Projects (Projects) and the three Shared Resource Cores (Cores)
with organizational support, professional project management, biostatistical expertise, data storage and sharing
solutions, and a governance framework. The Admin Core will plan and coordinate meetings between the
scientific teams, as well as between the scientific teams and the leadership groups. The Admin Core will include
a Project Manager, who will provide professional project management services to ensure that stated objectives
are successfully achieved. As part of this effort, the Project Manager will monitor Core activities to ensure that
efforts of these cutting-edge scientific resources are integrated and coordinated, and that the Cores are operating
effectively and efficiently to meet the needs of the Projects. The Project Manager will also establish a governance
framework for resolving potential conflicts between team members and for managing resource utilization and
budgetary concerns. The Admin Core will include a Biostatistics Unit that will be intimately involved in all
experimental design and data analysis. The Biostatistics Unit will be responsible for ensuring that all experiments
are sufficiently powered, and that the resulting data are analyzed using the most scientifically rigorous
approaches. Novel methods will be developed when needed. One faculty-level statistician will split their effort
between the Biostatics Unit and the bioinformatics team within the Tumor and Microenvironment
Heterogeneity Core, coordinating communication and the transfer of data between these data analytic groups.
Finally, the Admin Core will include a Data Curator who will help establish and oversee a centralized data-storage
system into which all data generated by the scientific teams will be deposited and properly annotated. This
resource will facilitate the integration of disparate datasets, as well as the exchange of data and reagents
between the Projects, the Cores, and the external research community, as appropriate. Thus, the specific aims
of the Admin Core are to: 1) provide overall organizational support including the coordination of meetings
between the Projects, the Cores, and the leadership committees, 2) provide project management services to
ensure that scientific objectives are achieved in an efficient and cost-effective manner, 3) provide biostatistical
expertise to ensure experimental rigor and reproducibility, and 4) create and manage a centralized data storage
and sharing system to enable data integration.

## Key facts

- **NIH application ID:** 10883574
- **Project number:** 5P01CA265762-02
- **Recipient organization:** SALK INSTITUTE FOR BIOLOGICAL STUDIES
- **Principal Investigator:** TONY R. HUNTER
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $195,148
- **Award type:** 5
- **Project period:** 2023-07-06 → 2028-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10883574

## Citation

> US National Institutes of Health, RePORTER application 10883574, Administrative and Biostatistics Core (5P01CA265762-02). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10883574. Licensed CC0.

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