# Biomarkers of Dietary Intake and Exposure Data Coordinating Center

> **NIH NIH U24** · DUKE UNIVERSITY · 2024 · $511,297

## Abstract

Project Summary/Abstract
The purpose of the Dietary Biomarker Development Centers (DBDCs) Consortium is to identify
biomarkers of dietary intake that can serve as independent markers of dietary intake and
complement current dietary intake assessment methods and the continually evolving evidence
base for addressing metabolic transformation of dietary constituents, especially the non-
nutrients by host and microbial metabolism. The Data Coordinating Center (DCC) aims to: 1)
provide a robust administrative management structure that enhances communication and
collaboration and improves the DBDC’s Consortium productivity and quality, 2) provide data
transfers, harmonization, integration, processing, and management, 3) develop a self-service
analytics platform and interactive reporting for users and conduct analyses, and 4) communicate
and disseminate knowledge within and beyond the Consortium. Operationally, the DCC will
develop manuals of operations, provide protocol training, establish and monitor timelines,
organize meetings with the Steering Committee (SC), NIDDK/USDA, and Data Safety and
Monitoring Board (DSMB). For data management, the DCC will establish a federally-compliant
online electronic data capture system to support the direct submission of data and a web-based
consortium communication and collaboration platform (CCCP) for secure data sharing and
dissemination of tools and results. The CCCP will have a link to access the self-service
analytics and interactive reporting to facilitate easy access to the data. The DCC will periodically
assess data quality, perform checks for data completeness, develop data documentation,
ensure protection of patient confidentiality, prepare reports for the SC and DSMB, and prepare
de-identified public use data files for submission into the NIDDK repository. Finally, the DCC will
provide thought leadership, biostatistical support, and methodological innovation to account for
the multi-faceted nature of dietary biomarker development, and facilitate the preparation and
dissemination of study results through multiple high-impact manuscripts and presentations. Our
team’s nationally recognized expertise in data management, harmonization, and coordination of
large networks, and our experience in biomarker research uniquely positions the DCRI to
provide all of the services and support required by the Consortium.

## Key facts

- **NIH application ID:** 10884409
- **Project number:** 5U24DK129557-04
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** Hrishikesh Chakraborty
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $511,297
- **Award type:** 5
- **Project period:** 2021-08-16 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10884409

## Citation

> US National Institutes of Health, RePORTER application 10884409, Biomarkers of Dietary Intake and Exposure Data Coordinating Center (5U24DK129557-04). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10884409. Licensed CC0.

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