PROJECT SUMMARY CORE B: Behavioral Economics and Intervention Science (BEIS) Core The Vermont Center on Behavior and Health (VCBH) is a multidisciplinary research center located at the University of Vermont (UVM) that investigates relationships between personal behavior and risk for chronic disease and premature death. The overarching aim of the VCBH Behavioral Economics and Intervention Science (BEIS) Core is to provide investigators with scientific and technical expertise and research infrastructure in the three key areas of Decision Making, Intervention Sciences, and Economic Modeling. We propose that Stacey Sigmon, PhD continue as BEIS Core Director. Our Decision-Making team has administered 1,192 comprehensive executive function batteries to 700 participants in studies led by 10 VCBH investigators, ranging from efforts to understand executive function among dysregulated children, loss aversion and delay discounting among smokers to factors underlying variability in response to interventions to manage type 1 diabetes in young people. Our Intervention Sciences Module has supported studies evaluating novel behavioral and pharmacological interventions in vulnerable populations, including interventions to treat PTSD among patients with OUD, engagement in cardiac rehabilitation following myocardial infarction, smoking cessation among pregnant women, utilization of contraceptive services by women with OUD, and technology-assisted interim buprenorphine dosing for individuals with OUD. The BEIS Economic Modeling team has supported investigators in examining the behavioral economic principles underlying problematic drinking among college students, cost savings from telehealth screening for diabetic retinopathy, the economic impact of sudden unexpected infant death, cost-effectiveness of onsite contraceptive services for women at risk for unintended pregnancy, financial incentives for smoking-cessation among pregnant women, and adherence to cardiac rehabilitation after myocardial infarction. Taken together, we are confident that continuation and further development of this core’s dedicated service modules and teams will contribute considerably to ensure the impact and sustainability of VCBH in advancing scientific knowledge and improving clinical care in behavioral health at local, national, and international levels.