# Neuropathology

> **NIH NIH P01** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $350,339

## Abstract

PROJECT SUMMARY—Neuropathology Core (Core D)
Core D is a Neuropathology Core that plays a vital role in the UCSF FTD PPG. FTLD neuropathology has
become increasingly exciting and complex, with major advances arising from work accomplished through this
PPG. In this renewal application, we propose to continue to cultivate a world-class FTLD-oriented
neurodegenerative disease brain bank at UCSF. The Neuropathology Core aims to: (1) Obtain and bank human
brain and spinal cord tissue for neuropathological characterization and research from patients and healthy
controls ascertained through the Clinical Core, (2) Render neuropathological diagnoses and enter findings into
a secure database, (3) Expand digital neuropathology and provide quantitative data to Project 2 (Molecular
Biomarkers), (4) Support PPG cores and projects with data and tissue, (5) Review tissue requests and distribute
specimens, (6) Train the next generation of FTD-focused basic and clinical scientists in neuropathology
principles and methods, and (7) Support neuropathologic methods innovation. These core functions will support
the aims of this PPG by providing final neuropathological diagnoses to all projects and by supplying brain tissues
and digital neuropathology data to Project 2. The core will also interact extensively with other cores. Overall, the
Neuropathology Core will help to further develop a unique bank of specially handled CNS tissues for ongoing
and future FTLD molecular, translational, clinico-pathological, and biomarker discovery research.

## Key facts

- **NIH application ID:** 10890579
- **Project number:** 5P01AG019724-22
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** WILLIAM W SEELEY
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $350,339
- **Award type:** 5
- **Project period:** 2002-09-01 → 2028-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10890579

## Citation

> US National Institutes of Health, RePORTER application 10890579, Neuropathology (5P01AG019724-22). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10890579. Licensed CC0.

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