# Research Core 2: Health and Mobility Measures Core (RC2)

> **NIH NIH P30** · DUKE UNIVERSITY · 2024 · $247,565

## Abstract

PROJECT SUMMARY – Health and Mobility Measures Core (HMC)
An important consideration for investigators undertaking studies relevant to the Center theme “To Understand
and Optimize Reserve and Resilience” is how to select and implement the most appropriate and meaningful
measures. The Health and Mobility Measures Core (HMC) will provide this service by serving as the central
resource for Center investigators seeking advice, mentoring, training, and equipment for valid, sensitive, and
reliable whole-person, non-molecular measures. A panel of 13 members, with complementary expertise in
measurement across multiple domains, comprises the Core. The HMC will provide highly integrated, customized
support to investigators supported by our Research Education Component (REC), Pilot/Exploratory Studies Core
(PESC), External Projects (EPs), and the larger Duke Community engaged by the Duke Older Americans
Independence Center. The Core will support investigators by meeting regularly, or as needed, throughout the
full spectrum of project development; from early phase planning, to final interpretation of findings, to subsequent
grant preparations to dissemination and/or implementation. These meetings will concurrently involve members
of the Molecular Measures and Analysis Cores to ensure maximal synergy. The HMC will address three Specific
Aims. Aim 1 - To provide centralized measurement expertise, available for consultation and mentoring to
advance our thematic investigations of physical reserve and resilience. Aim 2 - To develop measurement
protocols and train personnel in administration and data collection. Aim 3 - To identify gaps in reserve and
resiliency measures and develop and/or adapt innovative new measurement approaches for related outcomes.
Up to three REC Scholars and three PES awardees will be supported during the first year of funding. Members
of the HMC will also provide service to EPs, and propose an innovative Developmental Project to extend
measurement and predictive capacity of the electronic health record and other big administrative data sources.
Two successful past workshops are proposed again; one to provide training in physical performance and
functional testing, and one to provide training in ambulatory measurement and data collection, to augment the
measurement capabilities of our trainees. New measures will be added to the HMC website and the Duke Pepper
Center Study Dashboard will be developed and posted for users. The dashboard is an interactive data
visualization dashboard that gives OAIC investigators the opportunity to interact with aggregated biomarker and
physical performance data collected from OAIC-affiliated studies spanning three decades. The Dashboard will
provide OAIC investigators with preliminary data to use for grant applications as well as a large, well-curated
dataset for new analyses. The HMC will provide an invaluable service to the Center, which will lead to greater
understanding of reserve and resilience, and whi...

## Key facts

- **NIH application ID:** 10890668
- **Project number:** 5P30AG028716-19
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** Katherine Shepherd Hall
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $247,565
- **Award type:** 5
- **Project period:** 2006-09-15 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10890668

## Citation

> US National Institutes of Health, RePORTER application 10890668, Research Core 2: Health and Mobility Measures Core (RC2) (5P30AG028716-19). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10890668. Licensed CC0.

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