# Bioinformatics Core

> **NIH NIH U54** · VIRGINIA COMMONWEALTH UNIVERSITY · 2024 · $124,902

## Abstract

Project Summary/Abstract
The primary goal of the Bioinformatics Core of VCU’s U4HELPP is to provide data management, quality control,
reproducible analyses, data storage, and data sharing with the PDXNet network for all information generated by
our project. In addition, it will provide centralized bioinformatics, statistical and methodological support for the
two research projects, Pilot Project, and future projects that will build upon them. The Core will serve as the focal
point governing the experimental design, data management, and statistical analyses for the two research
projects. We will reach these goals through three aims. The first aim establishes the protocol to develop and
maintain a central data, resource, and sample management system that enables an interface between multiple
disciplines including genomics, basic science, and clinical medicine. This aim will ensure that all data and
analyses are of high quality, conform to good laboratory practices specifications, and are disseminated to all
PDXNet members in a timely fashion. The second aim will be to provide bioinformatics, statistics, and
methodological support from project initiation through completion and beyond. The third aim will improve quality
of analysis of sequencing data from minorities by constructing and applying the ancestry appropriate reference
genome. The Core includes members from the Department of Biostatistics at VCU, the Bioinformatics Shared
Resource and Cancer Informatics Shared Resource at Massey Cancer Center (MCC).

## Key facts

- **NIH application ID:** 10890849
- **Project number:** 5U54CA283762-02
- **Recipient organization:** VIRGINIA COMMONWEALTH UNIVERSITY
- **Principal Investigator:** Jinze Liu
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $124,902
- **Award type:** 5
- **Project period:** 2023-07-19 → 2028-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10890849

## Citation

> US National Institutes of Health, RePORTER application 10890849, Bioinformatics Core (5U54CA283762-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10890849. Licensed CC0.

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