PROJECT ABSTRACT In April 2022, the U.S. Food and Drug Administration (FDA) announced a proposed ban on menthol cigarettes and all characterizing flavors in cigars. African Americans have high rates of menthol cigarette and flavored cigar use, which likely contributes to their disproportionate experience of tobacco-related health conditions. In response to the FDA’s announcement, the tobacco industry and its sources promulgated disinformation in African American communities about the increased criminalization and police discrimination for using tobacco products when the rules are enforced. Although the FDA has stated that it cannot and will not enforce actions against individual consumers for possessing or using menthol cigarettes or flavored cigars, disinformation about the flavor ban and its harmful impacts continues spreading among African American communities. The proposed study seeks to develop and evaluate the effectiveness of multi-level, anti-disinformation messages (ADM) to disrupt the spread and mitigate the detrimental effects of disinformation about the FDA’s proposed ban on menthol cigarettes and flavored cigars. In Aim 1, we will employ community-based participatory research methods to develop and engage with an Expert Advisory Board (EAB) that will engage in shared decision-making and provide their perspectives on all study activities. In Aim 2, we will conduct formative research to a) characterize the tobacco industry and its operatives’ rhetoric about the consequences of the anticipated flavor ban and b) elicit AA/Bs’ knowledge and perceptions about the anticipated flavor ban. Aim 2 data will inform the development of the Intervention Mapping (IM) logic models that depict the behavioral and environmental risk factors and determinants of respondents’ flavor ban receptivity. In Aim 3, we will use of IM process to develop, pre-test, and refine the individual and community-level ADM and creative concepts among AA/B participants. Finally, in Aim 4, we will conduct a randomized treatment and control evaluation design to test the effectiveness of our individual and community-based ADM campaign on AA/Bs’ receptivity to the flavor ban and counter- industry beliefs. Knowledge gained from this study will inform the FDA’s Center for Tobacco Products Communication Office and state and local public health departments regarding salient messages to communicate about the flavor ban to AA/B and other vulnerable populations.