# Impact of dilated cardio myopathy mutations on cardiac myosin structure and function

> **NIH NIH R01** · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · 2024 · $92,718

## Abstract

The goal of this post-baccalaureate research supplement is to enhance the impact of the parent
R01 by supporting a highly motivated recent, University of Vermont Biological Sciences graduate
for a 2-year research experience. The proposed supplement experience is designed to provide
the candidate with the resources, mentorship, and skills required to complete an independent
research project, which is a logical extension of the aims of the parent R01. The proposed
project, described in the Research Plan, has been designed to give the candidate mentored,
first-hand experience in four phases of scientific research: 1) Rationale and experimental design;
2) reagent production and experimentation; 3) data analysis and interpretation, and; 4)
communication of results. In addition, the candidate will have the opportunity to gain expertise
in the pathogenic mechanisms of inherited cardiomyopathies, a critical area of human health,
prior to attending medical school in the Fall of 2025.

## Key facts

- **NIH application ID:** 10891132
- **Project number:** 3R01HL163585-02S1
- **Recipient organization:** PENNSYLVANIA STATE UNIV HERSHEY MED CTR
- **Principal Investigator:** David M Warshaw
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $92,718
- **Award type:** 3
- **Project period:** 2022-12-15 → 2026-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10891132

## Citation

> US National Institutes of Health, RePORTER application 10891132, Impact of dilated cardio myopathy mutations on cardiac myosin structure and function (3R01HL163585-02S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10891132. Licensed CC0.

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