# CIRI Oncology Research Alliance

> **NIH NIH UG1** · COMMONSPIRIT HEALTH RESEARCH INSTITUTE · 2024 · $734,304

## Abstract

The CommonSpirit Health Research Institute (CSHRI) (formerly known as CIRI) Oncology Research Alliance (CORA) seeks to continue to support and expand a community-based cancer research network, made up of community hospitals and cancer centers and incorporate best practices in enrolling patients to National Cancer Institute (NCI)-sponsored cancer control, prevention, and care delivery clinical trials and other human subjects’ studies. The specific aims are: to increase enrollment in cancer control, prevention, and care delivery clinical trials by providing access to a wide portfolio of high quality research studies that meet the needs of CORA’s representative populations, annually accruing 10% of new cancer cases within the populations served by the network; and identify, design, and implement Cancer Care Delivery Research (CCDR) that leads to improved models of care and translates to high-quality, value-based services throughout the oncology continuum. Applying CSHRI’s innovative, centralized, and standardized organizational research model encompassing a network of community cancer programs, CSHRI will continue to provide the necessary resources for amplifying clinical trials across the country. CORA’s geographic reach and involvement with multiple distinct Primary and Sub-Affiliates allow it to offer a wide portfolio of trials to large, established programs as well as representative populations. Applying best practices from CORA to all current and new Primary and Sub-Affiliates along with increased physician engagement will increase the number of patients screened and enrolled in clinical trials. Leveraging CommonSpirit Health’s (CommonSpirit) unique, well-positioned standard oncology electronic health records (EHRs), enterprise data warehouse, and analytics capability will continue to give CORA the depth of data and access to information needed to expand CCDR. CommonSpirit Health’s EHRs at CORA sites yield accessible data across the network that feeds into the data warehouse. CommonSpirit Health’s single network tumor registry database and EHR make CORA responsive to requests for data around patterns of care. Lastly, the advanced patient navigation, survivorship, and multidisciplinary conferences and disease site specific tumor boards already in place at all Primary and Sub-Affiliate sites will support this research. Expanding to additional health systems and sites, and adding new investigators as opportunities arise will increase the number of patients that CORA can screen for enrollment in cancer clinical trials. CORA’s Primary and Sub-Affiliates’ coordinators’ and navigators’ integrated efforts will be utilized to improve cancer control and prevention, detection, care delivery, and treatment for representative populations. Continued growth of CORA’s community partner networks, translation support, and nurse navigation training at all Primary and Sub-Affiliate sites will help eliminate barriers to care.

## Key facts

- **NIH application ID:** 10892043
- **Project number:** 5UG1CA189809-11
- **Recipient organization:** COMMONSPIRIT HEALTH RESEARCH INSTITUTE
- **Principal Investigator:** Shahzad Siddique
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $734,304
- **Award type:** 5
- **Project period:** 2014-08-01 → 2026-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10892043

## Citation

> US National Institutes of Health, RePORTER application 10892043, CIRI Oncology Research Alliance (5UG1CA189809-11). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10892043. Licensed CC0.

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