# COBRE Center for Central Nervous System Function

> **NIH NIH P30** · BROWN UNIVERSITY · 2024 · $1,196,250

## Abstract

The long-term goal of the COBRE Center for Central Nervous System Function is to develop a neuroscience
research center that provides research support to a wide array of neuroscience researchers at Brown
University and its affiliated hospitals and the Rhode Island neuroscience research community. Since we began
our COBRE in 2013, we have supported 13 Project Leaders and nine Pilot Project Leaders as they developed
their research and academic careers. Collectively, our supported cohort has been awarded nearly 20 R01 or
equivalent research grants, which along with other awarded grants has yielded more than $50 million in
external funding. Grants relevant to our COBRE received by members of our Research Cores have totaled
another $4 million. Of the 11 Project Leaders who served two or more years, nine have successfully graduated,
with a tenth having received positive reviews of an R01 grant proposal. Collectively, our COBRE supported
scientists have published nearly 130 peer-reviewed papers citing COBRE support and more than 400 papers
overall. These papers have appeared in prestigious journals, including Nature Human Behavior, Current
Biology, Neuron, eLife, PLoS Computational Biology, Journal of Neuroscience and other field-specific journals.
We have developed a research core to assist our community in best practices for experimental design and
data analysis. The main objective for Phase 3 COBRE support relates to building-out our research core to
serve the needs of the neuroscience community at Brown and Rhode Island and also to expand and
strengthen our Pilot Project Program. We will enhance the scope of our Research Core by integrating two
existing neuroscience core facilities, the MRI Research Facility and the Rodent Behavior Phenotyping Core,
into one administrative entity. Additionally, we will partner with service cores of other local COBREs and those
at Brown-affiliated hospitals to broaden our service outreach. Our vision is that by sustaining and transitioning
the established research infrastructure into an integrated entity, we will enable neuroscientists to conduct their
work more effectively and efficiently.

## Key facts

- **NIH application ID:** 10892788
- **Project number:** 5P30GM149405-02
- **Recipient organization:** BROWN UNIVERSITY
- **Principal Investigator:** JEROME N SANES
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,196,250
- **Award type:** 5
- **Project period:** 2023-08-01 → 2028-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10892788

## Citation

> US National Institutes of Health, RePORTER application 10892788, COBRE Center for Central Nervous System Function (5P30GM149405-02). Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/grant/nih/10892788. Licensed CC0.

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