SCIENTIFIC AND TECHNICAL CORE: PROJECT SUMMARY The Scientific and Technical (Sci-Tech) Core integrates computing and information technologies, along with services, funding, and training, to establish a versatile and economically viable infrastructure that promotes groundbreaking population research, especially among junior population scientists (including both assistant and associate professors). The landscape of technologies and data sources in the population sciences is evolving rapidly, often outpacing the rate at which we formulate and address inquiries in population health and demography. Our challenge lies in efficiently supporting existing research practices while effectively embracing and sharing new advancements in both science and technology. This strategic approach aims to enhance the mission of the PSC by incorporating and disseminating innovative research directions. The specific aims are to: a) to maintain an advanced computing infrastructure that supports cutting-edge population-related research conducted within the PSC; b) develop and implement efficient protocols to (1) establish effective communication channels and statistical support among investigators working across multiple research fields; (2) integrate innovative tools and technologies to enhance data collection, including surveys, biomarker/anthropometric/genetic ancestry measures, and linkages to register and/or geospatial data; and (3) implement secure data sharing practices that comply with regulatory requirements while facilitating collaboration and data access; c) encourage active participation from the PSC research community in an ongoing synthesis of advancement in computing technology and computational methodology; and d) enhance research community access to shared computing resources by making all the services offered by the Sci-Tech core available to affiliates and visitors associated with the local partnerships and sponsored research affiliation program developed by the PSC, including access to the RDC, weekly colloquiums, and bi-weekly workshops.