# The Early Detection Research Network: Data Management and Coordinating Center

> **NIH NIH U24** · FRED HUTCHINSON CANCER CENTER · 2024 · $8,752,632

## Abstract

Project Summary
The key for the Early Detection Research Network (EDRN)'s success lies in good communication among
scientists in multiple disciplines; efficient evaluation and prioritization of promising biomarkers; and rigorous
validation studies to demonstrate their clinical utility. The overall aims of the proposed renewal of the Data
Management and Coordinating Center (DMCC) are to (i) provide coordination of EDRN in order to enhance
communication and collaboration among EDRN investigators and with general scientific communities; (ii)
coordinate EDRN validation studies and provide leadership in data science; (iii) disseminate cancer biomarker
information to broader scientific communities and the public; and (iv) manage the EDRN Core funds. Under the
direction of the EDRN Steering Committee, the DMCC will 1) perform network coordination and outreach and
promote collaborations among scientific investigators by providing support for EDRN meetings and workshops,
developing and maintaining EDRN secure websites and listservs, producing and maintaining all EDRN
documents, and maintaining the online review system for applications submitted to the EDRN; 2) support
EDRN validation studies by developing and maintaining validation study data management systems; working
with EDRN investigators on study design, protocol development, data forms, and study manuals; coordinating
and monitoring studies; tracking specimens; and performing QA/QC and study evaluation; and provide and
promote best statistical and computational practices to EDRN studies; 3) work with the NCI and JPL to provide
informatics resources for the EDRN Secure Web site for data security, data warehousing, and data sharing,
and a Public Web site for dissemination; and 4) work closely with the EDRN SC and the NCI Project
Coordinator and Fred Hutch OSR to timely activate the core funds after the EDRN SC approval and ensure the
compliance of all regulatory requirements for sub-award management.

## Key facts

- **NIH application ID:** 10894693
- **Project number:** 5U24CA086368-24
- **Recipient organization:** FRED HUTCHINSON CANCER CENTER
- **Principal Investigator:** RUTH D ETZIONI
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $8,752,632
- **Award type:** 5
- **Project period:** 2000-04-14 → 2027-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10894693

## Citation

> US National Institutes of Health, RePORTER application 10894693, The Early Detection Research Network: Data Management and Coordinating Center (5U24CA086368-24). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10894693. Licensed CC0.

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