# Experimental Mouse Shared Resource (EMSR)

> **NIH NIH P30** · UNIVERSITY OF ARIZONA · 2024 · $188,007

## Abstract

EXPERIMENTAL MOUSE SHARED RESOURCE: ABSTRACT
The goal of the Experimental Mouse Shared Resource (EMSR) is to enhance the productivity and capabilities
of University of Arizona Cancer Center (UACC) Members by providing access to in vivo models, including
immunocompromised and genetically engineered mouse (GEM) models. EMSR also provides comprehensive
support of experimentation in rodents (mouse and rat) and offers effective and efficient services that allow
UACC Members to avoid duplication of equipment and training that would occur without such a Shared
Resource. Importantly, EMSR ensures the reproducibility of technical interventions and provides the rigorous
quality control that is required to complete informative analyses of animal studies. The primary services offered
by EMSR are organized into two functional units: (1) a GEM Production Unit, and (2) the Experimental Rodent
Unit. Services are completely complementary and together generate impactful research and help secure
funding for UACC Members. Additional services associated with GEM generation include the transfer of mouse
strains for cryopreservation and consulting on troubleshooting for genotyping and breeding strategies. Services
offered for rodent experimentation include the inoculation of various xenograft and orthotopic tumor models
and the expertise to perform services ranging from routine injections to technically challenging surgical
procedures. EMSR performs all aspects of experimentation from developing genetic models of cancer,
injecting tumor cells, treating and measuring tumors for drug testing, and processing tissues for experimental
endpoints, including gross pathologic examinations with cryopreservation of organs/tissues and preparation of
tissue for examination by UACC Members and other Shared Resources. In CY20, EMSR provided services to
101 unique users. Of these, 56 (55%) were UACC Members and 45 (45%) were non-Members, including eight
(8%) external users. UACC Member usage included 30 users (54%) from the Cancer Biology Program, 19
users (34%) from Clinical & Translational Oncology, and 7 (12%) users from the Cancer Prevention & Control
Program. EMSR contributed to 53 peer-reviewed publications and provided support to 222 grant applications
over this period. EMSR is in compliance with the University’s Biosafety Committee rules and the Rodent
Experimentation is good laboratory practice qualified.

## Key facts

- **NIH application ID:** 10896011
- **Project number:** 5P30CA023074-43
- **Recipient organization:** UNIVERSITY OF ARIZONA
- **Principal Investigator:** Noel Andrew Warfel
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $188,007
- **Award type:** 5
- **Project period:** 1997-07-01 → 2027-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10896011

## Citation

> US National Institutes of Health, RePORTER application 10896011, Experimental Mouse Shared Resource (EMSR) (5P30CA023074-43). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10896011. Licensed CC0.

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