PROJECT SUMMARY The Administrative Core will provide oversight, management, and logistical support for our U19 Research Team and Overall Program, collaborate with the Somatic Cell Genome Editing (SCGE) Translational Coordination and Dissemination Center (TCDC), and foster engagement with the other Research Teams in the SCGE Consortium. The Core will ensure that the U19 Research Team is best positioned to successfully achieve the Project annual milestones, provide administrative support for project and grant management, establish and maintain the infrastructure for transparent and secure recordkeeping, and facilitate formal and ad hoc meetings within the U19 Research Team and interactions with the SCGE Consortium and TCDC.