# The Stanford Clinical Center for the Study of Type 1 Diabetes in Acute Pancreatitis

> **NIH NIH U01** · STANFORD UNIVERSITY · 2024 · $255,390

## Abstract

Project Summary/Abstract
The Stanford Clinical Center applies to participate in the Type 1 Diabetes in Acute Pancreatitis
Consortium (T1DAPC), to contribute its established clinical and research infrastructure in acute
pancreatitis and expertise in pancreatology, endocrinology, and immunology. Our group is well-
positioned to develop a prospective cohort of patients with acute pancreatitis to support human based
studies investigating the relationship of diabetes, with a particular focus in Type 1 diabetes mellitus
(T1D), in acute pancreatitis. In response to the research objectives of the T1DAPC as outlined in this
RFA, we have formed a strong complementary scientific team. Our proposal is highly responsive to
the RFA in several specific ways. The Stanford Clinical Center has the capacity and infrastructure to
effectively recruit patients into this prospective cohort of acute pancreatitis patients. Second, We
propose to use prospectively collected bio-specimens from this cohort to examine the role of the
immune system in acute pancreatitis and its relationship to the development of diabetes. Third, we
propose to look at hormonal changes associated with post-pancreatitis diabetes (PPDM) as well as
the potential relationship between PPDM and exocrine pancreatic insufficiency. The opportunity to
pursue these investigations in collaboration with other centers as a Consortium is an exciting novel
opportunity to study acute pancreatitis and its relationship with type 1 diabetes.

## Key facts

- **NIH application ID:** 10896401
- **Project number:** 5U01DK127395-05
- **Recipient organization:** STANFORD UNIVERSITY
- **Principal Investigator:** Marina Basina
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $255,390
- **Award type:** 5
- **Project period:** 2020-09-18 → 2025-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10896401

## Citation

> US National Institutes of Health, RePORTER application 10896401, The Stanford Clinical Center for the Study of Type 1 Diabetes in Acute Pancreatitis (5U01DK127395-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10896401. Licensed CC0.

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