# Developmental & Career Enhancement Core

> **NIH NIH U54** · H. LEE MOFFITT CANCER CTR & RES INST · 2024 · $177,110

## Abstract

PROJECT SUMMARY – DEVELOPMENTAL CORE
The overarching goal of the Developmental Core (DC) for the Partnership to Assess Viral and Immune
Landscape Intersections with Oncology for People Living with HIV (PAVILION) is to enhance capacity for HIV-
associated cancer research through fostering the career development of junior investigators in South Africa,
Zimbabwe, and the United States who have a demonstrated interest in infection-related cancer research among
people living with HIV (PLWH). This goal involves two broad strategies: 1) implementing a program that
generates and supports rigorous pilot research projects and 2) providing other training and educational resources
to enhance skills necessary for long term career success. This strategy represents a shift in the culture of
research at PAVILION partnering low- and middle-income country (LMIC) institutions. The momentum created
by this strategy would provide significant incentive for junior investigators at these sites to take advantage of pilot
research funding opportunities while consolidating efforts to pursue career development within a supportive
environment with highly experienced mentors, ensuring their long-term success as independent researchers.
Moreover, this pipeline of highly trained researchers with interest in infection-related cancers among PLWH will
meet the critical need for transdisciplinary, multi-institutional, and international partnerships to understand and
potentially mitigate the rapidly growing cancer burden in Africa, where the prevalence of HIV infection remains
high. The PAVILION DC program will help ameliorate this growing public health crisis by supporting junior
investigators who can lead and maximize the rigor of future research focused on cancers occurring among
PLWH1-4 and ensure sustainability of research capacity, strength, and commitment.
The Specific Aims to achieve this goal are:
Aim 1: Competitively award innovative infection-related cancer pilot research projects across the cancer
continuum among PLWH (Area 1) This aim provides funding for junior investigators and mentoring by
experienced senior scientists and clinicians.
Aim 2: Implement educational and career development activities that enhance the capacity to conduct
rigorous infection-related cancer research focused on PLWH (Area 2) This aim provides education,
workshops, courses, and career development activities for PAVILION junior investigators.

## Key facts

- **NIH application ID:** 10898574
- **Project number:** 5U54CA277834-02
- **Recipient organization:** H. LEE MOFFITT CANCER CTR & RES INST
- **Principal Investigator:** Margaret Ziona Borok
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $177,110
- **Award type:** 5
- **Project period:** 2023-08-03 → 2028-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10898574

## Citation

> US National Institutes of Health, RePORTER application 10898574, Developmental & Career Enhancement Core (5U54CA277834-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10898574. Licensed CC0.

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