# MUSC Specialized Center of Research Excellence on Sex Differences Renewal 2022

> **NIH NIH U54** · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2024 · $1,495,542

## Abstract

ABSTRACT
The MUSC Specialized Center of Research Excellence (SCORE) on Sex Differences in substance use disorders
and the relationship between stress and relapse has been highly productive for 20 years. In addition to coalescing
a multidisciplinary group of investigators across different disciplines working closely together to explore sex and
gender differences in substance use disorders and the relationship between stress and drug use, the MUSC
SCORE has provided a fertile training ground for new investigators and attracted senior investigators to apply
their skills to sex- and gender-specific research. During the proposed renewal period, we will continue to reach
across the MUSC campus, state of South Carolina, and nationwide through cross-SCORE collaborations and
other initiatives focused on dissemination of research findings to improve health outcomes. The science within
our research group also will grow with four tightly integrated research projects. To address critical public health
needs, the proposed research projects will investigate sex differences in cannabis use disorders across the
lifespan, focusing on populations (emerging adults, postpartum women, and older adults) with recent rapid
increases in cannabis use and potential vulnerability to sex disparate harms of cannabis. The specific aims of
this SCORE are to support and enhance translational scientific collaborations among the investigators
conducting primary and pilot research projects, catalyze further growth of interdisciplinary sex- and gender-based
research on the MUSC campus, continue foundational research training for Early Career Investigators dedicated
to sex and gender-focused translational research, and promote strategic partnerships to enhance the translation
and dissemination of SCORE findings and other relevant research to improve health outcomes.

## Key facts

- **NIH application ID:** 10898731
- **Project number:** 5U54DA016511-22
- **Recipient organization:** MEDICAL UNIVERSITY OF SOUTH CAROLINA
- **Principal Investigator:** Kevin M. Gray
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,495,542
- **Award type:** 5
- **Project period:** 2002-09-01 → 2028-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10898731

## Citation

> US National Institutes of Health, RePORTER application 10898731, MUSC Specialized Center of Research Excellence on Sex Differences Renewal 2022 (5U54DA016511-22). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10898731. Licensed CC0.

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