# University of Wisconsin Prostate SPORE

> **NIH NIH P50** · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $2,085,688

## Abstract

PROJECT SUMMARY
The University of Wisconsin (UW) Prostate Cancer SPORE is a highly collaborative research proposal that links
basic scientists with prostate cancer clinicians to advance treatment strategies for prostate cancer patients. The
broad objectives of this SPORE are to: 1) Increase multidisciplinary translational research and develop the next
generation of prostate cancer researchers, 2) Develop common resources to promote advances, 3) Translate
promising new approaches into patients, and 4) Improve overall survival and quality of life for patients with
prostate cancer. A crosscutting theme that encompasses this SPORE is understanding tumor resistance in
advanced prostate cancer and exploiting this knowledge to improve patient outcomes. The UW Prostate Cancer
SPORE has three primary research projects: 1) Tumor Microenvironment Initiators of the Metastatic Cascade in
High-Risk Prostate Cancer, 2) Androgen Deprivation as an Immune Modulating Therapy in Combination with
Targeted Immunotherapy of Prostate Cancer, and 3) Extending Clinical Benefit by Selective Treatment of
Resistant Lesions in mCRPC. The SPORE will support this research with three Cores (Administrative, Integrated
Pathology Radiology, and Biostatistics and Bioinformatics). The Career Enhancement Program and
Developmental Research Program will engage new and established investigators and further translational goals
in a rich multidisciplinary environment. When completed, the research of the UW Prostate Cancer SPORE will
advance our treatments and understanding of prostate cancer and undoubtedly beneficially impact patients with
this disease.

## Key facts

- **NIH application ID:** 10899409
- **Project number:** 5P50CA269011-02
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** DAVID F. JARRARD
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $2,085,688
- **Award type:** 5
- **Project period:** 2023-07-01 → 2028-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10899409

## Citation

> US National Institutes of Health, RePORTER application 10899409, University of Wisconsin Prostate SPORE (5P50CA269011-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10899409. Licensed CC0.

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