PROJECT SUMMARY The Administrative Core will provide the scientific leadership and operational structure necessary for the planning, implementation, management, and supervision of all activities of the University of Wisconsin Prostate Cancer SPORE. Embedded within the University of Wisconsin Carbone Cancer Center (UWCCC) Office for Translational Research Services (OTRS), the Administrative Core will centrally provide a wide variety of administrative coordination, oversight, and research support services to all leaders, co-leaders, investigators and core directors. It will offer these services in a centralized manner, to promote efficiency and ensure that all SPORE research and activities are focused, connected, that complex scientific objectives are met, and existing cancer center resources are utilized and not duplicated. The Administrative Core will also provide the oversight, monitoring and auditing required to ensure projects are meeting translational endpoints and reach human application within five years, consistent with the SPORE mission. Specific Aims of the Administrative Core are: 1) Leadership (scientific leadership); 2) Administrative management; 3) Planning and evaluation activities; 4) Institutional support (management of unencumbered institutional resources provided); 5) Integration of SPORE within UWCCC, UW-Madison, and regional partnership alliances; 6) Prostate cancer patient population (efforts to increase diversity in clinical and translational research populations); 7) Data management; and 8) Communications.