The Neuroscience Roadmap Scholars (RMS) Program at the University of Alabama at Birmingham (UAB) has experienced a great amount of success, since its inception 2014. The RMS Program targets the obstacles impeding success with the goal of increasing the number of trainees with varied life experiences, perspectives and viewpoints by providing them with the necessary tools and skills early in their PhD careers essential to making neuroscience research a life-long career choice. The specific “value added” components of the Program include the annual southeast regional NEURAL summer conference for UAB students and neuroscience doctoral students from across the country, interactions with Career Coaches who provide support separate from the Scholar’s Research mentor, team building retreats, peer-to peer mentoring and undergraduate mentoring, and distinct curricular and extracurricular activities. With continued investment in Neuroscience at UAB by the Heersink School of Medicine, the future of the Neuroscience RMS Program is secure, and scholars will benefit from the vibrant neuroscience environment that has attracted $96M in extramural funding. Success of the Program during the second award period is substantiated by the greater than expected enrollment and participation by students training in neuroscience at UAB, the success in securing extramural fellowship awards by Scholars, and the 83% matriculation of graduates to postdoctoral fellowships compared to 67% of other biomedical science students. Goals for the next funding period are informed by this success, and input from Scholars, Career Coaches, and internal and external evaluation.