# Developing Innovative Tools To Overcome Factors that Limit Outcomes for All Women and Disparities for BAA women

> **NIH NIH P50** · MAYO CLINIC ROCHESTER · 2024 · $364,575

## Abstract

PROJECT SUMMARY – PROJECT 3
The goal of the COllaboration for EQuity in Uterine Leiomyomas (COEQUaL) Project 3 is to develop
innovative technology to identify women with uterine fibroids early for intervention/prevention and to predict
the re-intervention rate after therapeutic options, while ensuring the implementation of such technology is
acceptable to women with UF. The specific aims of Project 3 are: 1) to develop, validate, and assess the
portability of EHR risk prediction models for incident symptomatic fibroids, 2) to characterize patients for whom
genetic information improves upon an EHR-based fibroid prediction risk model. 3) to identify factors associated
with hysterectomy and the effect of uterine-conserving therapies that allow for the prevention of hysterectomy.
Stakeholder input will be sought throughout the project to assess the acceptability of implementation of EHR-
based technology including genetic data and risk prediction models. Given the major health and healthcare
disparities seen in women with fibroids, and especially Black/African American women with fibroids, the
evaluation and decision-making for therapy should be standardized, equitable, and accessible to all women.
The findings of this COEQUaL project will change the clinical paradigm for clinical care by creating tools for
healthcare providers systems to empower personalized and evidence-based decision making for women with
fibroids.

## Key facts

- **NIH application ID:** 10899982
- **Project number:** 1P50HD115283-01
- **Recipient organization:** MAYO CLINIC ROCHESTER
- **Principal Investigator:** Shannon Kathleen Laughlin-Tommaso
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $364,575
- **Award type:** 1
- **Project period:** 2024-06-19 → 2029-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10899982

## Citation

> US National Institutes of Health, RePORTER application 10899982, Developing Innovative Tools To Overcome Factors that Limit Outcomes for All Women and Disparities for BAA women (1P50HD115283-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10899982. Licensed CC0.

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