# Validating an Administrative Claims Based Case Definition for Traumatic Brain Injury

> **NIH NIH R00** · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $246,510

## Abstract

Project Summary/Abstract
 The population of older adults living with traumatic brain injury (TBI) has increased precipitously in the
last decade. Current clinical care guidelines for TBI do not offer any specific recommendations for the clinical
care of older adults, despite substantial evidence that primary injury mechanisms and secondary injury sequela
are markedly different in older as compared to their younger counterparts. In addition to increased rates of
incident TBI in this age cohort, many individuals who have sustained TBI earlier in life are surviving to older
age and living with chronic disability from their injuries. There is a need for research to better understand the
short-term and longer-term clinical care needs for older persons living with TBI. Existing hospital-based
registries and TBI cohort studies have limited information on health care use after discharge from acute and
post-acute health care settings; therefore, our current knowledge of health care needs for older adults living
with TBI are confined by these limitations. The use of Medicare data linked to existing research cohorts is
widely practiced in other biomedical fields, but these linkage methods are under-utilized in TBI research.
 The overall objectives of this K99/R00 proposal are to characterize the health, function, and clinical
care pathways among older adults with TBI by leveraging Medicare claims combined with multiple data
resources, including: the National Trauma Databank, Health and Retirement Study, and TBI Model Systems
National Database. The K99 specific aims are: 1) to identify prognostic characteristics associated with the
proportion of time spent in different health care settings in the first year after post-acute TBI care admission,
and 2) to compare function, health, and health care utilization and cost among current older adults with remote
TBI exposure, incident TBI in later life, and no history of TBI. 3) During the R00 portion of the grant, we will
use probabilistic matching to link the TBI Model Systems National Database with Medicare claims to develop a
rich new infrastructure that will support future investigation into associations between rehabilitation care
utilization patterns and longitudinal patient-reported TBI outcomes among current older adults with TBI. This
innovate research exploits unique strengths from multiple complementary existing data resources in hospital
and community-based settings to address novel TBI rehabilitation-relevant questions.
 The proposed research and training plan will address the following knowledge gaps during the K99
period: 1) training in analysis of administrative claims and cost data, 2) analysis of population-based databases
for rehabilitation research, 3) training in data linkage and harmonization, 4) understanding the health care
experiences of older adults with TBI and their caregivers, and 5) refining skills in grant writing. The knowledge
gained from the proposed research and training is signifi...

## Key facts

- **NIH application ID:** 10904790
- **Project number:** 5R00HD106060-04
- **Recipient organization:** ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- **Principal Investigator:** Raj Gopalan Kumar
- **Activity code:** R00 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $246,510
- **Award type:** 5
- **Project period:** 2021-09-07 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10904790

## Citation

> US National Institutes of Health, RePORTER application 10904790, Validating an Administrative Claims Based Case Definition for Traumatic Brain Injury (5R00HD106060-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10904790. Licensed CC0.

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