# NCI SBIR Contract Topic 428 Phase II (Solicitation Number: BAA 75N91022R00027): Cloud-based Liquid-biopsy and Radiomics Platform for the Cancer Research Data Commons

> **NIH NIH N44** · EARLYDIAGNOSTICS, INC. · 2023 · $1,994,911

## Abstract

Integrative analysis of multi-omics datasets is revolutionizing cancer research and patient care. To take advantage of the full breadth of CRDC’s petabyte-scale data, EarlyDx will seamlessly integrate its liquid biopsy cloud-computing platform with CRDC data repositories. Liquid biopsies provide a non-invasive approach for interrogating the genomic and epigenomic profiles of tumors. Co-analysis of CRDC datasets with userprovided data from a tube of blood will ensure broad user adoption of the CRDC. To that end, in Phase I, EarlyDx has developed a prototype that successfully integrates its informatics tools with the CRDC multi-omics datasets through the DCF. The goal of this Phase II project is to finalize the Phase I prototype and expand the prototype to integrate imaging data in the CRDC and implement deep learning tools for integrative multi-omics and radiomics analysis. Specifically, we will conduct the following aims: 1) finalize the Phase I prototype for multi-omics analysis; 2) expand the platform for CRDC imaging data analysis; 3) implement integrative analysis tools; 4) implement diagnostic tools; 5) recruit at least 100 users for usability testing. Our platform with CRDC integration will accelerate cancer research and promote clinical applications such as cancer detection and treatment in broad populations.

## Key facts

- **NIH application ID:** 10906504
- **Project number:** 75N91023C00022-0-9999-1
- **Recipient organization:** EARLYDIAGNOSTICS, INC.
- **Principal Investigator:** CHUN-CHI (JIM) LIU
- **Activity code:** N44 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $1,994,911
- **Award type:** —
- **Project period:** 2023-08-15 → 2025-08-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10906504

## Citation

> US National Institutes of Health, RePORTER application 10906504, NCI SBIR Contract Topic 428 Phase II (Solicitation Number: BAA 75N91022R00027): Cloud-based Liquid-biopsy and Radiomics Platform for the Cancer Research Data Commons (75N91023C00022-0-9999-1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10906504. Licensed CC0.

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