# Oklahoma Shared Clinical and Translational Resources

> **NIH NIH U54** · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2024 · $3,999,999

## Abstract

The primary mission of the Oklahoma Shared Clinical and Translational Resources (OSCTR) is to improve
health by catalyzing clinical and translational research (CTR) that addresses the top health concerns
experienced in the state. The OSCTR integrates health professionals, investigators, and scientific resources at
more than 30 public, private, and tribal partners statewide to fulfill its mission. Several features make
Oklahoma an ideal setting to continue and expand these efforts, including high rates of chronic diseases and
large rural and tribal populations where improved outcomes may serve as models across IDeA states.
Oklahomans have the sixth lowest life expectancy in the US, with widening disparities for American Indians
and rural populations leading to early mortality. Cancer, diabetes, cardiovascular disease, arthritis, and
autoimmunity are top causes of enhanced morbidity or disability and are exacerbated by high rates of tobacco
and other substance abuse and low rates of routine health screening and healthy life choices. Research on the
health priorities and health equity of our tribal and other underserved populations has been fostered by strong
relationships between research institutions and tribal nations and rural communities. The OSCTR has helped
build a growing and diverse cadre of investigators who have launched independent CTR careers and is broadly
supported by institutional leaders committed to CTR and improving Oklahomans’ health. The OSCTR houses a
highly productive Clinical Resources Core with a CAP-certified biorepository and cutting-edge resources for
clinical data research. Concurrent with these strengths, the OSCTR has leveraged partnerships to build
networks for practice-based research to help speed the adoption of evidence-based practices in patient care.
Despite our successes, the sustainability of CTR research in Oklahoma and its impact on public health are
limited by ongoing needs for infrastructure support and clinical research investigators. To support rural and
tribal health equity, the OSCTR will assist tribal health systems in building CTR infrastructure, foster
interactions via the Tribal Engagement Unit, and expand research with community organizations to address
social determinants of health and increase opportunities for clinical trial participation. We will continue to
support the development of junior investigators from many disciplines by providing training, mentoring, pilot
grants, biostatistics/epidemiology expertise, access to patient samples and clinical data, study recruitment and
regulatory assistance, and comprehensive online resources. We will engage health professionals, communi-
ties, and patients in high-priority CTR through an online portal and existing networks of community-oriented
health improvement organizations. We will continue work with Oklahoma IDeA programs and the national
IDeA-CTR network to develop and share effective infrastructure and increase opportunities for Oklahomans to
pa...

## Key facts

- **NIH application ID:** 10908678
- **Project number:** 5U54GM104938-12
- **Recipient organization:** UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- **Principal Investigator:** JUDITH A JAMES
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $3,999,999
- **Award type:** 5
- **Project period:** 2013-09-01 → 2028-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10908678

## Citation

> US National Institutes of Health, RePORTER application 10908678, Oklahoma Shared Clinical and Translational Resources (5U54GM104938-12). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10908678. Licensed CC0.

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