# The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

> **NIH NIH U01** · ECOG-ACRIN MEDICAL RESEARCH FOUNDATION · 2024 · $349,468

## Abstract

ABSTRACT National Cancer Institute (NCI) supported clinical trials (CTs) are key drivers of innovations in cancer care; however limited participation in NCI-supported CTs reduces reach and thus some are not able to fully benefit from cutting edge treatments and precision medicine. CT participation continues to fall short and the multitude of structural, clinical, physician, and patient barriers warrant multilevel interventions to enhance referral and enrollment to NCI-supported CTs. The ECOG-ACRIN Cancer Research Group (EA), as an NCORP Research Base, has engaged community providers and researchers through a robust research portfolio that spans Cancer Control, Cancer Prevention, and Cancer Care Delivery. We propose to leverage the collective resources of the EA, our team’s decades of work on improving participation in clinical trials, and our foundational work in patient navigation and CT research literacy tools to create and evaluate an ECOG-ACRIN Trial SUPPORT Toolkit (SUPPORT intervention) that aims to improve referral and enrollment in active NCI-supported therapeutic trials. The multilevel EA SUPPORT intervention consists of a CT research literacy tool and CT Resource Navigators who will interface with patients, providers, and community oncology site staff to improve referral and enrollment to CTs.

## Key facts

- **NIH application ID:** 10909090
- **Project number:** 5U01CA274996-03
- **Recipient organization:** ECOG-ACRIN MEDICAL RESEARCH FOUNDATION
- **Principal Investigator:** Elyse R. Park
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $349,468
- **Award type:** 5
- **Project period:** 2022-09-15 → 2028-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10909090

## Citation

> US National Institutes of Health, RePORTER application 10909090, The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials (5U01CA274996-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10909090. Licensed CC0.

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