# Epigenetic & Genomics

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2024 · $203,116

## Abstract

Project Summary Core C 
A major goal in diabetes research is to understand how alterations in the epigenome and subsequent 
responses in gene expression impact disease phenotype and treatment regimens. The objective of the 
Epigenetic and Genomics Core (EGC) is to provide cutting-edge, reliable and innovative genomic technologies 
to support the diabetes and related endocrinology and metabolism research goals of DRC investigators. It also 
offers training, education and consultation in genomics technologies in order to enhance the ability of DRC 
Investigators to implement these technologies in their research. The EGC will provide the following services: 
Technical Support For Sequencing-Based Assays: The Core will provide technical support for high- 
throughput sequencing assays on Illumina sequencing platforms (MiSeq, HiSeq2500, HiSeq4000, NovaSeq 
6000), enabling RNA sequencing (RNA-seq), low-input RNA-seq, microRNA sequencing (miRNAseq), Global 
Run- On sequencing (GRO-Seq), ribosome profiling and deep sequencing (Ribo-Seq), Chromatin 
Immunoprecipitation linked to massively parallel sequencing (ChIP-Seq), Assay for Transposase- Accessible 
Chromatin with high throughput sequencing (ATAC-Seq), Cross-Linking Immunoprecipitation (CLIP-Seq), Hi-C, 
MethylC-sequencing, metagenomic assays, and sequencing of CRISPR Screens. 
Single Cell Sequencing Assays: The Core will provide technical support for single cell sequencing assays, 
including 10X Genomics Chromium Single Cell Solution technologies, and implementation of new technologies 
as they arise. 
Training and Consultation: The Core will provide consultation and training of students, postdoctoral fellows, 
investigators and technical staff regarding high-throughput sequencing methodologies and data analysis. 
These functions will be overseen by the Functional Genomics Specialist. 
Bioinformatics Support: The Core will provide bioinformatics support for assistance with experimental 
design, choice of technological platform, data analysis and data quality control.

## Key facts

- **NIH application ID:** 10909256
- **Project number:** 5P30DK063491-22
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** SVEN W HEINZ
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $203,116
- **Award type:** 5
- **Project period:** 2002-12-01 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10909256

## Citation

> US National Institutes of Health, RePORTER application 10909256, Epigenetic & Genomics (5P30DK063491-22). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10909256. Licensed CC0.

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