# PDX Core

> **NIH NIH U54** · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2024 · $48,050

## Abstract

PDX CORE PROJECT SUMMARY
The goals of the PDTC PDX Core are to establish and maintain PDX lines for the purpose of conducting animal
preclinical trials using experimental and standard-of-care therapeutics; to promote quality control, reproducibility,
and collaboration by developing and maintaining shared Standard Operating Procedures (SOPs) for PDX
development, maintenance, experimentation, and pathogen testing; to provide infrastructure to manage large PDX
collections and to generate, store, and manage PDX-based experimental data generated by the projects; to
facilitate exchange of PDX models between the PDXNet program; and to facilitate transfer of experimental data
to the PDTC Bioinformatics Core and the PDTC PDXNet Data Commons and Coordinating Center to relate
treatment responses to the molecular characteristics of individual patients’ tumors. Our PDTC PDX Core current
comprises 262 breast PDX lines available for projects within our PDTC Center and across the PDXNet program.

## Key facts

- **NIH application ID:** 10909328
- **Project number:** 5U54CA224076-06
- **Recipient organization:** UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH
- **Principal Investigator:** Michael T. Lewis
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $48,050
- **Award type:** 5
- **Project period:** 2017-09-25 → 2028-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10909328

## Citation

> US National Institutes of Health, RePORTER application 10909328, PDX Core (5U54CA224076-06). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10909328. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*