SUMMARY: BSL-3 PRACTICES AND WORKFORCE DEVELOPMENT CORE The BSL-3 Practices and Workforce Development Core (BSL-3 PWD) shall develop and maintain SOPs, biosafety and biosecurity plans and provide training for BSL-3 best practices to ensure a safe and secure work environment within the University of Louisville (UofL) Regional Biocontainment Laboratory (RBL). The BSL-3 PWD Core will support the RBL’s mission to provide a regional resource to facilitate research goals for biodefense, emerging infectious diseases, and pandemic preparedness and response. The Core will provide BSL-3 practices training to investigators at UofL, regional academic investigators with BSL-3 facilities, and specialized biosafety and biocontainment professionals and tradesmen who support the operations the UofL RBL and the RBL network. The specific aims of the BSL-3 PWD core to: (1) Provide laboratorians and personnel training for BSL-3 best practices to ensure a safe and secure work environment within the RBL and support the RBLs mission; (2) Develop and maintain Standard Operating Procedures (SOPs) for personnel working in the BSL-3/ABSL-3 space in the RBL, (3) Provide select agent training for handling of select agents, inventory, and accountability; (4) Provide Operations and Maintenance training for specialized biosafety and biocontainment professionals and tradespeople who support the operations of the RBL; and (5) Provide biosafety education and training for removal of materials and equipment from the BSL-3, policies for shipping and receiving materials, and waste management.