# Training Core

> **NIH NIH P50** · UT SOUTHWESTERN MEDICAL CENTER · 2024 · $159,598

## Abstract

Project Summary/Abstract
The techniques of CRISPR/Cas9-mediated genomic editing and the ability to generate induced
pluripotent stem cells (iPSCs) from a sample of a patient’s blood have placed medicine on the brink of a
revolution in our ability to treat, and perhaps even cure, a broad range of genome-based diseases. Over
the past four years the Wellstone Muscular Dystrophy Cooperative Research Center at the University of
Texas Southwestern Medical Center (now the UTSW Wellstone MDSRC) has made tremendous strides
toward the translation of this technology to benefit patients with Duchenne muscular dystrophy, and
ultimately, other forms of muscular dystrophy. The mission of the Training Core has been just as
impactful as it is essential to train a new generation of clinicians, physician-scientists, and basic scientists
who are able to apply these evolving technologies in the service of muscular dystrophy patients and their
community. The objective of the training core is to enhance the educational environment of the Wellstone
network in order to recruit, train, and maintain the next generation of transformative investigators focused
on addressing the challenges of muscular dystrophy. Our approach focuses on five elements: (Aim 1)
To enhance the training environment of the UTSW Wellstone Center and promote trainee career
advancement, (Aim 2) To recruit new trainees to muscular dystrophy research, (Aim 3) To mentor
trainees in the process of obtaining funding support for the next step in their careers, (Aim 4) To organize
research meetings involving Wellstone trainees, and (Aim 5) To organize training activities that benefit
the overall muscular dystrophy research community. To accomplish these goals, we’ve built on the very
successful program developed over the past four years of funding, that has both complemented and
leveraged the strengths of existing training programs here at UTSW.

## Key facts

- **NIH application ID:** 10911065
- **Project number:** 5P50HD087351-10
- **Recipient organization:** UT SOUTHWESTERN MEDICAL CENTER
- **Principal Investigator:** Beverly A Rothermel
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $159,598
- **Award type:** 5
- **Project period:** 2015-09-15 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10911065

## Citation

> US National Institutes of Health, RePORTER application 10911065, Training Core (5P50HD087351-10). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10911065. Licensed CC0.

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