The Oklahoma Rheumatic Disease Research Cores Center (ORDRCC) facilitates, supports, and grows collaborative rheumatic disease research through fostering junior rheumatic disease investigator career development, forging national collaborations, making available cutting-edge technologies, and providing well- phenotyped clinical data and biospecimens to understand the pathogenesis, prediction, prevention, and precision treatment of rheumatic diseases. These goals are being met and have resulted in the successful launch of at least 33 new rheumatic disease investigator careers (local and distant), new or renewed collaborative, multi-investigator NIH rheumatic disease research grants, increasing collaborations, novel NIH- funded and investigator-initiated clinical trials with partnered mechanistic studies, and enhanced diversity in rheumatic disease research and researchers. The ORDRCC includes individuals from numerous scientific and clinical disciplines, spanning 26 current center investigators, 22 junior center investigators (12 local, 10 distant) and 12 nominated Scholars. The Administrative Core serves as the ORDRCC centralized governing resource and a liaison between the ORDRCC leadership, the Research Cores, all Center Investigators, and the Advisory Committee. The main purpose of Admin Core is to develop new rheumatic disease investigators through local and distant Junior Center Investigator and Scholars programs which expand use of our patient collections and clinical data, as well as access to advanced technologies. We propose a new structured pipeline program to provide early exposure to rheumatic disease patients and investigation to trainees spanning from undergraduates to housestaff. We will also augment a multi-faceted Enrichment Program with weekly seminars and an annual all-day symposium with new web-enabled workshops for professional development, a new Scientific Writing Success Center, and an expanded formalized mentor-development program. The Administrative Core also serves as the primary communication hub for the ORDRCC. Based upon input from our patient advisors, we propose to expand communication with our patients and their advocates, as well as broaden communication to our new external partners, outside JCIs/Scholars and the broader scientific community. The ORDRCC will expand Core and Collection use and outreach through collaborations with other Center awards. Finally, the Administrative Core will provide oversight, management, and prioritization of resources, ensure regulatory compliance, and grant management oversight and serve as the nidus for interactions with the Advisory Committee which is inclusive of Internal and External members to ensure suggestions are vetted and implemented. This Core will also provide the overall Leadership and oversight for the Center. The ORDRCC will use annual evaluations and assessments, both qualitative and quantitative, to ensure the Center is meeting goals and to help prioritize resources,...