# Improving Patient-Centered Decision-Making for Stress Urinary Incontinence Treatment in Older Men

> **NIH NIH K76** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $243,000

## Abstract

PROJECT SUMMARY/ABSTRACT
This is a Beeson K76 career development award for Dr. Lindsay Hampson, a clinician investigator with a
background in ethics, health services research, and stress urinary incontinence (SUI). Dr. Hampson is
pivoting her career towards aging, with a goal of becoming a national leader in geriatric urology research
focused on achieving goal-concordant care for older adults with urologic issues that affect quality of life (QOL)
through reducing treatment disparities and improving treatment decision-making. This proposal seeks to
improve goal-concordant management for post-prostatectomy SUI among older adults by: 1) identifying
drivers of disparities in the care of older post-prostatectomy men, 2) determining treatment preferences and
priorities of this patient population, and 3) promoting individualized evaluation and treatment decision-making
in the context of geriatric-informed health and values. Significance: Post-prostatectomy SUI significantly
impacts QOL, disproportionately impacting older men. Despite a focus on reducing treatment of prostate
cancer, one quarter of men 65-75 years of age diagnosed with prostate cancer will still undergo prostatectomy.
An estimated 25-30% of men are using pads, diapers, or complaining of bothersome incontinence beyond one
year following prostatectomy, and these rates likely represent underestimation of continence rates in older
men. SUI surgery has been shown to result in near-term QOL improvements with high satisfaction rates, yet is
severely underutilized and delayed, and men facing treatment decisions have substantial decisional regret. In
Aim 1’s national cohort study using Veterans Affairs and Medicare data, we aim to identify factors associated
with post-prostatectomy SUI under-treatment and treatment delays among older men. In Aim 2’s discrete
choice experiment survey of older post-prostatectomy men, we aim to identify patient-centered SUI treatment
priorities and understand how these preferences vary based on characteristics associated with access to care.
These data will be utilized to develop an Incontinence Post-Prostatectomy Assessment & Decision Support (I-
PADS) tool which will be evaluated in Aim 3 through a mixed methods study and feasibility/acceptability trial.
Mentoring team: Dr. Hampson’s exceptional multidisciplinary mentoring team is led by Dr. Louise Walter, an
internationally recognized expert on individualized decision making for in older adults. This award will support
Dr. Hampson’s transition to aging research through dedicated training in 1) conducting national cohort
studies of older adults, 2) developing expertise in measuring treatment preferences, 3) implementation science
theory and methods to implement interventions for older adults, and 4) leadership in geriatric urology to
become a leader in goal-concordant urologic care among older adults by reducing treatment disparities and
improving treatment decision-making. Next Steps: These results will serve as ...

## Key facts

- **NIH application ID:** 10911350
- **Project number:** 5K76AG079091-02
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** Lindsay Ann Hampson
- **Activity code:** K76 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $243,000
- **Award type:** 5
- **Project period:** 2023-09-01 → 2028-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10911350

## Citation

> US National Institutes of Health, RePORTER application 10911350, Improving Patient-Centered Decision-Making for Stress Urinary Incontinence Treatment in Older Men (5K76AG079091-02). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10911350. Licensed CC0.

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