SUMMARY/ABSTRACT - ADMINISTRATIVE CORE The NEI funded P30 University of Michigan Vision Research Center provides priority access to resources and services to NEI-R01 funded investigators in five areas representing critical needs that are beyond the resources of individual laboratories. These areas include: Advanced Statistical Analysis, Instrument Fabrication, Visual Functional Assessment, Molecular Biology Instrumentation and Stem Cell Biology Facilities, and Morphology and Imaging. The services also help provide other researchers, especially those preparing NEI R01 proposals, those with other NEI research awards, and those collaborating with NEI-funded researchers to generate critical preliminary data to apply for NEI R01 awards. The Cores, with available time, can also be used by other individuals involved in vision research or new investigators to encourage pursuit of novel vision-related research. The University of Michigan Vision Research Center (UMVRC) is directed by David A. Antonetti, Ph.D., Professor of Ophthalmology and Visual Sciences, Roger W. Kittendorf Research Professor of Ophthalmology and Visual Sciences and Scientific Director of the Kellogg Eye Center. Dr. Antonetti has had continuous NEI support for 24 years to explore the mechanisms of retinal vascular permeability in diabetic retinopathy and other blinding eye diseases, develop novel therapies to regulate signaling pathways that control vascular permeability and explore methods for restoration of vascular function. Dr. Antonetti has recently accepted the role of PI and Director of the P30 Vision Research Center. As Director of the Administrative Core, Dr. Antonetti will be responsible for ensuring that Vision Research Center activities are appropriate to the needs of vision researchers, and that they are run efficiently and according to appropriate priorities. Dr. Antonetti will work closely with Departmental financial officers to ensure responsible oversight of Core expenditures and budget. Dr. Antonetti will review the Center’s website information, organize and run quarterly meetings of the UMVRC Executive Committee to discuss Core operations and services and he will prepare, analyze, and report the results of surveys and questionnaires designed to ensure that Core resources and services are appropriate to the needs of vision scientists and are operated in an effective and efficient manner. Finally, Dr. Antonetti will ensure progress reports are prepared and provided to the NIH in a timely manner. He is assisted by a Research Program Manager and Grant Administrator in the Department of Ophthalmology and Visual Sciences. Overall supervision of the Vision Research Center is under the direction of the PI and the UMVRC Executive Committee, which meets quarterly. This committee consists of the PI, who serves as Chair as well as the Scientific Director for Research in the Department of Ophthalmology and Visual Sciences, and the 5 Core Directors and 5 co-Directors. The quarterly...