The North Carolina Central University (NCCU) seeks competitive renewal of its RCMI - Center for Health Disparities Research (RCHDR) to continue enhancing NCCU's research ecosystem to develop investigators who are conducting impactful and cutting-edge research to address health disparities (HD). The Center is an interdisciplinary effort at NCCU housed at the Julius L. Chambers Biomedical/Biotechnology Research Institute (BBRI), an institute opened in 1999 to pursue research afflicting populations in NC and to train the research workforce. In this renewal application, a concerted effort was made to establish a robust leadership team for the RCHDR through a group of senior- and mid-level experienced individuals. The Center will be comprised of four Cores: Administrative Core (AC); Research Capacity Core (RCC) (arranged into 5 sub-cores); Investigator Development Core (IDC) and Community Engagement Core (CEC) supporting one basic and one behavioral full biomedical research project plus pilot studies.