# Administrative Core

> **NIH NIH U54** · UNIVERSITY OF TX MD ANDERSON CAN CTR · 2024 · $236,843

## Abstract

Administrative Core (Core A) SUMMARY
The Administrative Core, led by Dr. Jeffrey Myers and Dr. Vlad Sandulache, and supported by the Center
Administrator Dr. Toyin Babarinde, is an indispensable component of the Houston Center for Acquired Resistance
Research (H-CARR). The overall objective of the Administrative Core (Core A) is to provide critical centralized
support to the H-CARR and ensure seamless interactions and integration between the three projects and cores
within the center as well as the broader ARTNet community. Core A is designed to monitor research activity and
provide stable and continuous leadership that guides future scientific directions for this Research Center. Core
A will leverage the wide-ranging scientific, research related experience of the Center Advisory Group in critical
decision-making steps. The Administrative Core will ensure an emphasis on basic mechanistic and translational
research and facilitate interdisciplinary and inter-project integration, including assistance in the establishment of
collaborations with other ARTNet centers as well as the U24 ARTNet Coordinating Data and Management Center
(ARTNet CDMC U24) and NCI staff. Core A will also have overall responsibility for fiscal and budgetary
management of the H-CARR, including the employment of key personnel to ensure a highly qualified, well
trained, managed, and diverse work force that will enable cost-effective and efficient use of resources. This
Core will also monitor scientific integrity and overall compliance with all institutional, state, federal, and NCI
regulations and requirements, as well as quality assurance for data integrity. The strength of Core A rest in its
well-developed structure of intra-programmatic, intra-institutional, and external advisors who are all dedicated to
support Core A Leaders through ongoing review, advice, and periodic meetings and recommendations to ensure
robust scientific performance and progress toward the agreed upon programmatic goals. Under the direction of
the Core A Leaders, Core A will also provide support and infrastructure for research, facilitate clear and open
communications among all H-CARR investigators, provide a centralized resource for regulatory monitoring and
compliance activities, and perform scheduled reviews of project and core activities and progress towards their
goals. Under the direction of the Core A Leaders, Core A will also provide support and infrastructure for research,
facilitate clear and open communications among all H-CARR investigators, engage in regulatory monitoring to
optimize the successful outcome of the basic mechanistic and preclinical/translational research in resistance to
drug therapy in head and neck cancer.

## Key facts

- **NIH application ID:** 10917406
- **Project number:** 5U54CA274321-03
- **Recipient organization:** UNIVERSITY OF TX MD ANDERSON CAN CTR
- **Principal Investigator:** Jeffrey Nicholas Myers
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $236,843
- **Award type:** 5
- **Project period:** 2022-09-20 → 2027-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10917406

## Citation

> US National Institutes of Health, RePORTER application 10917406, Administrative Core (5U54CA274321-03). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10917406. Licensed CC0.

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