# Improving awareness of women with hypertension: ROAR (Rural, Obese, At Risk)

> **NIH NIH U54** · AUGUSTA UNIVERSITY · 2024 · $1,469,903

## Abstract

More than 1 in 3 women are living with heart disease and many are unaware of the risks. Hypertension is a major
modifiable risk factor for cardiovascular disease (CVD), and ~47% of adults in the US have hypertension. In
~85% of cases, the cause of hypertension is unknown and only ~50% of patients taking medication achieve
blood pressure (BP) control to recommended levels. A critical barrier to limiting premature death from CVD is
lack of awareness surrounding the risks of CVD. Our location in the Southeast of the US will contribute to our
impact. The prevalence of hypertension and obesity are high in GA, MS, and SC. The prevalence of hypertension
and associated risk is not equal among all populations. Indeed, the prevalence of hypertension in Black people
in the US is among the highest in the world. Our overall goal is to transform academic and community
understanding of sex as a biological variable (SABV) in the consideration of hypertension. We will accomplish
this through the creation and dissemination of innovative educational content, the development of strategic
partnerships, and enhanced community engagement in the Southeast of the US. This SCORE is designed to
provide novel insight into the mechanisms controlling BP in females vs. males, develop a comprehensive
educational platform on SABV in CVD extending from grade school to medical school, and increase awareness
and education of CVD and the risks of uncontrolled hypertension in women across the health span through
community outreach. This SCORE has 4 objectives. Objective 1 is to conduct cutting edge research to advance
our understanding of sex-specific mechanisms that control BP to limit cardiovascular risk. Objective 2 is to
develop a culturally diverse research pipeline of biomedical scientists trained in the field of SABV in CVD.
Objective 3 is to establish a community outreach pipeline of trained scientists to increase awareness of SABV
and promote optimal cardiovascular healthcare for men and women. Objective 4 is to empower the community
to self-monitor and work to identify barriers to improving access to healthcare. The outcomes of our proposed
SCORE include not only advances in science and training of the next generation of leaders in the study of the
impact of biological sex on the development and progression of CVD, but also the development of a range of
educational content that will be fully available to the Consortium. This will include 1) the development educational
materials by medical illustrators for students/trainees at all stages, the community, and physicians, 2)
establishing a SABV Mentoring Academy, 3) creating a SABV curriculum and workshop for students, fellows,
and junior investigators. The impact of our work will be to increase recognition and awareness of the risks of
CVD and hypertension to women across their health span and best practices for SAVB experimental design.
Our comprehensive community outreach plan will also be critical to reach a highly at-risk ...

## Key facts

- **NIH application ID:** 10918123
- **Project number:** 5U54HL169191-02
- **Recipient organization:** AUGUSTA UNIVERSITY
- **Principal Investigator:** Jennifer C Sullivan
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,469,903
- **Award type:** 5
- **Project period:** 2023-09-01 → 2028-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10918123

## Citation

> US National Institutes of Health, RePORTER application 10918123, Improving awareness of women with hypertension: ROAR (Rural, Obese, At Risk) (5U54HL169191-02). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10918123. Licensed CC0.

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