# Core B: Biospecimen and Pathology

> **NIH NIH P50** · FRED HUTCHINSON CANCER CENTER · 2024 · $289,593

## Abstract

PROJECT SUMMARY/ABSTRACT
The Specimen Core provides part of the infrastructure support for the major projects comprising the PNW
Prostate Cancer SPORE as well as for future pilot and developmental projects. It has been designed to meet
the needs of these projects and serve as a stand-alone resource for collaborative efforts with other SPOREs.
This Core will provide a well-organized and standardized system of specimen collection, storage, distribution,
and related clinical/research information dissemination that is based on over two decades of experience. There
will be consistency and quality assurance in the pathological analysis of tissue specimens. This Core has 5
components:
1. Clinical specimen acquisition (i.e. tissues, including those from surgery and the rapid autopsy program,
 serum, plasma, and urine), processing, quality control, storage, distribution, and database entry;
2. A development program to continually improve the quality and efficiency of biospecimen acquisition,
 processing, and storage to increase the fidelity of specimens provided to the SPORE investigators;
3. Maintain prostate cancer xenograft lines established by the Core and make specimens available for biological
 study and/or perform pre-clinical studies for SPORE investigators and collaborators;
4. Laboratory services, including production of tissue microarrays, interpretation of immunohistology by urologic
 pathologists, and production of specimen derivatives for research;
5. An administrative program to obtain samples from minorities, prioritize the distribution of specimens, ensure
 patient confidentiality and compliance with IRB requirements, continually improve quality control measures,
 and interact with other SPOREs.

## Key facts

- **NIH application ID:** 10919800
- **Project number:** 5P50CA097186-23
- **Recipient organization:** FRED HUTCHINSON CANCER CENTER
- **Principal Investigator:** Colm M Morrissey
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $289,593
- **Award type:** 5
- **Project period:** 2002-09-19 → 2028-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10919800

## Citation

> US National Institutes of Health, RePORTER application 10919800, Core B: Biospecimen and Pathology (5P50CA097186-23). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10919800. Licensed CC0.

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