# A commercialized platform for diversified large-scale chronic electrophysiology

> **NIH NIH R44** · SPIKEGADGETS, LLC · 2024 · $1,016,232

## Abstract

PROJECT SUMMARY
Chronic multichannel electrophysiology is a critical tool for examining how behavior arises from
the complex interconnected activity of the brain. The goal of this project is to provide a commercial
ecosystem for multi-electrode array (MEA) manufacturers to scale their products to many more
electrodes than they currently offer. By commercializing a compact 512-channel integrated
circuit—the EChip—we will offer a path for MEA manufacturers to integrate electronics directly
onto their arrays, thereby sidestepping the need for bulky connectors or electronics. We aim to
enable the availability of diverse types of electrodes, all with increased channel counts, to satisfy
the diverse needs of experimenters. Furthermore, by developing versatile electronics and
powerful software to interface with the EChips, the EChip-enabled MEAs will be usable in diverse
behavioral paradigms and species.

## Key facts

- **NIH application ID:** 10921067
- **Project number:** 1R44MH136865-01
- **Recipient organization:** SPIKEGADGETS, LLC
- **Principal Investigator:** Peter Denes
- **Activity code:** R44 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,016,232
- **Award type:** 1
- **Project period:** 2024-07-16 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10921067

## Citation

> US National Institutes of Health, RePORTER application 10921067, A commercialized platform for diversified large-scale chronic electrophysiology (1R44MH136865-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10921067. Licensed CC0.

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