# Viral Testing

> **NIH NIH U42** · UNIVERSITY OF PUERTO RICO MED SCIENCES · 2024 · $775,532

## Abstract

PROJECT SUMMARY/ABSTRACT:
Continuous testing for certain viruses that can compromise HIV research results, is essential in any SPF Program
used for this purpose. The CPRC-SPF colony is free and systematically assayed for Simian immunodeficiency
virus (SIV), Type D Simian retrovirus (SRV-D) and Simian T-lymphotropic virus (STLV-1). The colony is also
free of Herpes B virus, which represents an occupational health risk for the personnel handling the animals. The
primary purpose of the virology testing arm of CPRC-SPF breeding program is to assure that its Indian-origin
rhesus macaque colony, supporting NIH-sponsored research specially on HIV/AIDS, is free of the above-
mentioned viruses. An advantage of this program is that it has been closed to external individuals since 2016.
Certainly, this aspect substantially decreases the risks of the re-introduction of any of the four tested viruses from
an external source. The specific aim of the Viral Testing Core is: Sustain the implementation of the reliable viral-
testing algorithm to continue producing high quality SPF animals with a well-defined virological status in
support of PHS-NIH sponsored biomedical research, especially HIV/AIDS studies.

## Key facts

- **NIH application ID:** 10921895
- **Project number:** 2U42OD021458-23
- **Recipient organization:** UNIVERSITY OF PUERTO RICO MED SCIENCES
- **Principal Investigator:** CARLOS A SARIOL
- **Activity code:** U42 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $775,532
- **Award type:** 2
- **Project period:** 2016-07-01 → 2028-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10921895

## Citation

> US National Institutes of Health, RePORTER application 10921895, Viral Testing (2U42OD021458-23). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10921895. Licensed CC0.

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