# Novel Self-closing 12F Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Transcatheter Edge-to-Edge Repair (TEER) Technique Via Femoral Vein Access.

> **NIH NIH SB1** · MEDFREE, INC. · 2024 · $275,530

## Abstract

Project Summary
The MEDFREE® Valve Repair System will innovatively improve upon the current market leading MitraClip
device, while leveraging and building on the proven Transcatheter Edge-to-Edge Repair technique. We aim to
address this vastly unmet percutaneous structural heart market by delivering a simpler, easier-to-use device in
a smaller 12F catheter system that can be used by a single operator. MEDFREE has already completed
preclinical GLP studies in porcine model (Cohort A: n=2, 30 days; Cohort B: n=5, 140 days) with outstanding
results. MRI and Durability (fatigue) studies were also completed with outstanding results. We are now seeking
funds via NIH Commercialization Readiness Program, in preparation for EFS/FIH clinical studies.

## Key facts

- **NIH application ID:** 10922576
- **Project number:** 1SB1HL174244-01
- **Recipient organization:** MEDFREE, INC.
- **Principal Investigator:** Raghuveer Basude
- **Activity code:** SB1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $275,530
- **Award type:** 1
- **Project period:** 2024-04-01 → 2026-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10922576

## Citation

> US National Institutes of Health, RePORTER application 10922576, Novel Self-closing 12F Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Transcatheter Edge-to-Edge Repair (TEER) Technique Via Femoral Vein Access. (1SB1HL174244-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10922576. Licensed CC0.

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