# Core B: Data and Research Methods

> **NIH NIH P20** · RHODE ISLAND HOSPITAL · 2024 · $355,842

## Abstract

Project Summary
Despite their public health significance, interventions focusing on opioid use disorder and overdose often suffer
from a lack of rigorous design and evaluation. Throughout phase II of the COBRE on Opioids & Overdose, the
Data and Research Methods (DRM) Core will continue to support COBRE project leaders and pilot investigators
in overcoming the methodological, analytical, and translational challenges that have traditionally stymied
research project success and public health impact. By providing quantitative expertise, research infrastructure,
and technological resources, the DRM Core greatly strengthens the rigor of the work produced by COBRE
investigators, enhances their data use/management capacity, and provides training opportunities relevant to the
entire research to practice pipeline. DRM Core services include: 1) methodological consultation on study design
issues such as sampling, matching, survey development, and data harmonization; 2) biostatistical support, such
as the use of statistical models, model-building procedures, model specification, and methods to handle missing
data; 3) “dashboarding” and other visualization services to generate user-friendly, interactive data outputs for
dissemination and translation of information; 4) providing a HIPAA-compliant data management system which
will provide multi-tier access, back-ups, and de-identification; 5) providing access and linkage to statewide
overdose-related databases, as well as record matching services to enrich outcomes across projects; and 6)
providing training on and facilitating the exchange of methodological, computational, and analytic ideas related
to the study of overdose and opioid-related harms. In phase II, the DRM Core will offer expertise on best practices
for centering racial/ethnic health equity throughout all stages of the research process, and will support
investigators as they apply open science principles to their work.
DRM Core Director Dr. Brandon Marshall is an established CDC- and NIH-funded investigator with extensive
experience in cohort study design, survey development, and the use of advanced quantitative methods, including
simulation approaches, to evaluate non-randomized public health interventions. His leadership will be
supplemented by highly trained staff with expertise in epidemiological methods, project management, database
development, programming, data visualization, and biostatistics.

## Key facts

- **NIH application ID:** 10923911
- **Project number:** 5P20GM125507-07
- **Recipient organization:** RHODE ISLAND HOSPITAL
- **Principal Investigator:** Brandon David Lewis Marshall
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $355,842
- **Award type:** 5
- **Project period:** 2018-09-01 → 2028-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10923911

## Citation

> US National Institutes of Health, RePORTER application 10923911, Core B: Data and Research Methods (5P20GM125507-07). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10923911. Licensed CC0.

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