# Core A:  Administration

> **NIH NIH P50** · BOSTON UNIVERSITY MEDICAL CAMPUS · 2024 · $286,420

## Abstract

ADMINISTRATIVE CORE – ABSTRACT
The Contraception Research Center at Boston University School of Medicine (BUSM-CRC) brings together an
experienced team of clinical, industrial and basic scientists to develop and test a new contraceptive product, ZB-
06, a vaginal film that releases an antisperm antibody, Human Contraception Antibody (HCA). HCA was
originally isolated from the blood of an infertile but otherwise healthy woman and targets an antigen on sperm to
effect rapid sperm agglutination and immobilization. Success of the BUSM-CRC relies upon an Administrative
Core that provides scientific and administrative leadership in coordinating the two contraception development
research projects and one contraceptive translational research project that make up the program. The
Administrative Core will also maintain the clinical database and provide statistical services, and coordinate data
and materials acquisition and sharing so that the research progresses in an integrated iterative fashion to meet
individual project and programmatic milestones,
The Specific Aims of the Administrative Core are:
1. To provide scientific leadership and administrative oversight. Specifically, the Administrative Core will
establish an Executive Committee (EC) for ongoing assessment of project and core milestones, resource
allocation and changes to the experimental design. The Administrative Core will also convene an external
Scientific Advisory Panel (SAP) to review the program annually. The Administrative Core will facilitate
communication through scheduled conference calls and investigator meetings, provide financial and
administrative support, and insure adherence to institutional and federal guidelines.
2. To coordinate data and materials acquisition and sharing to insure that project and program
milestones are met. The Administrative Core will be responsible for the reagent/research material and data
management and sharing plan, and for monitoring milestone achievements.
3. To manage the clinical database and statistical analysis for the two clinical trials.

## Key facts

- **NIH application ID:** 10923980
- **Project number:** 5P50HD096957-07
- **Recipient organization:** BOSTON UNIVERSITY MEDICAL CAMPUS
- **Principal Investigator:** Deborah J Anderson
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $286,420
- **Award type:** 5
- **Project period:** 2018-09-14 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10923980

## Citation

> US National Institutes of Health, RePORTER application 10923980, Core A:  Administration (5P50HD096957-07). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10923980. Licensed CC0.

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