# Core Grant for Vision Research - Core 3

> **NIH NIH P30** · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $119,292

## Abstract

CORE 3: ANIMAL MODELS AND EYE ORGAN CULTURE
ABSTRACT
The goal of the Animal Models and Eye Organ Culture Core is to facilitate the use of animals and eye organ
culture to study visual function and visual diseases by qualifying NEI funded researchers. We also assist non-
qualifying investigators in generating preliminary data, in support of proposals seeking NIH funding. This is
accomplished by providing expertise in complementary animal models across a range of species from rodents
to non-human primates (NHPs) and including spontaneous and experimental models of glaucoma, retinal
degeneration, ocular vascular disease ocular pharmacology and toxicology and infectious diseases and
includes animal handling and anesthesia and, importantly, provision of alternatives to live animal research
including eye organ culture. We provide expertise and equipment necessary for the evaluation of visual
system structure and function including ERG, multifocal and pattern ERG, VEP, OCT, retinal imaging,
tonometry and outflow facility and outflow pathway determination. As a result of unique expertise and access to
model species spanning the translational spectrum, this core has had a broad impact, facilitating
interdisciplinary and inter-institutional vision research in support of the NEI’s mission.

## Key facts

- **NIH application ID:** 10924075
- **Project number:** 5P30EY016665-18
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** Colleen Mary McDowell
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $119,292
- **Award type:** 5
- **Project period:** 2005-07-01 → 2028-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10924075

## Citation

> US National Institutes of Health, RePORTER application 10924075, Core Grant for Vision Research - Core 3 (5P30EY016665-18). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10924075. Licensed CC0.

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