Program Summary-Abstract The overall goals of the CA-NARCH Administrative Core are to support the educational and research efforts of the CA-NARCH Student Development Program and to provide critical ongoing community- based participatory tribal direction. The administrative structure of the CA-NARCH has evolved through funding from NARCH III, NARCH V, NARCH VII, and NARCH X and consists of the IHC Executive Team, Dan Calac PI, Stephanie Brodine Program Director, Corinne Davidson/McDaniels Research Director, and the CA-NARCH Tribal IRB. The CA-NARCH CORE supports the center components to fulfill the overall NARCH mission to implement health research projects prioritized by the area tribes, reduce mistrust in research among AI/AN, enhance the research capacity and partnerships to reduce AI/AN health disparities, and develop a cadre of AI/AN health research professionals. The CA-NARCH is based at Indian Health Council (IHC), and non-profit clinic that supports a consortium of 9-tribes in San Diego County. The CA NARCH XI Administrative Core will help fulfill the major aims and goals of all Center components by pursuing the following specific aims: 1) To provide leadership and management, including administrative and fiscal oversight of the CA-NARCH student development project; 2) To coordinate communication and dissemination of information between the local tribes, tribal leaders, and the student development program team; 3) To support the cultural interface and augment research ethical training in the SDP with biannual workshops led by the Tirbal IRB chair and members; 4) To seek out and disperse information on funding opportunities through NARCH and other sources for continued development of training and mentoring programs and/or research projects; 5) To evaluate progress of the CA-NARCH in achieving its objectives and milestones. The specific aims will support the efforts of the CA-NARCH mission of conducting highly relevant, American Indian/Alaskan Native (AI/AN) community-based research and establishing a trained cohort of AI/AN scientists dedicated to impacting the health disparities of AI/AN populations. Activities in the CA-NARCH are also evaluated by the CA-NARCH IRB, which is officially registered with the U.S. DHHS Office of Human Subjects Research Protection (OHRP) as #IRB000041401 and has received Federal-wide Assurances approval under Indian Health Council, Inc., and is registered as #FW00006757. This work shall also strive to establish a replicable model partnership for tribal nations and academic organizations.