# Bioinformatics and Biostatistics Core

> **NIH NIH P20** · TULANE UNIVERSITY OF LOUISIANA · 2024 · $166,293

## Abstract

ABSTRACT (Bioinformatics and Biostatistics Core)
The growing availability of large-scale, high-dimensional molecular information and clinical research data, as
well as sophisticated statistical methodologies for analyzing these complex data, provides unprecedented
opportunity to advance clinical and translational research of cardiometabolic disease. However, extensive
study design, bioinformatics, biostatistics, and computational expertise is needed to appropriately incorporate
these cutting-edge advancements into biomedical research. As part of the proposed Centers for Biomedical
Research Excellence (COBRE) Phase 2 grant, we will establish a new Bioinformatics and Biostatistics
Core (BBC) that will serve as a hub for study design, bioinformatics, biostatistics, and computational support.
The overall objectives of the BBC are: 1.) To expand study design, bioinformatics, biostatistics, and
computational resources, capacity, and support in the COBRE program through the establishment of a
dedicated analytic and computational infrastructure; and 2.) To train and assist research project leaders
(RPLs), pilot project leaders (PPLs), other COBRE investigators, and collaborators in the application of
sophisticated bioinformatics and biostatistics approaches that promote high-quality research. To achieve these
objectives, the BBC will provide RPLs, PPLs, other COBRE investigators, and collaborators with the support in
study design, bioinformatics, and biostatistics that is needed to conduct high-quality clinical and translational
research of cardiometabolic disease (Aim 1). Furthermore, we will leverage our expertise in bioinformatics and
biostatistics to develop and implement novel tools and methods that are tailored to Research Projects of RPLs,
PPLs, other COBRE investigators, and collaborators and may be adapted and adopted by the Tulane scientific
community. As part of Aim 2, the BBC will provide training opportunities to RPLs, PPLs, other COBRE
investigators, and collaborators seeking to broaden and enhance their clinical and translational research skills.
Our proposed workshops and one-on-one mentorship opportunities will build bioinformatics, biostatistics, and
computational research skills, empowering COBRE investigators and collaborators to independently conduct
rigorous clinical and translational research in cardiometabolic disease. To ensure continued visibility and
utilization of the BBC beyond the COBRE funding period, we will also establish a self-sustaining BBC that will
serve as a long-term resource for the Tulane University scientific community (Aim 3). Our self-sustaining core
facility will be supported by NIH-funded research studies, as well as fee-based services for non-COBRE
investigators. In total, the BBC is a critical component of the COBRE Phase 2 program, which will be
extensively utilized by all four proposed COBRE Research and Pilot Projects. The BBC will provide Tulane
investigators with the supports necessary to accelerate s...

## Key facts

- **NIH application ID:** 10927214
- **Project number:** 5P20GM109036-08
- **Recipient organization:** TULANE UNIVERSITY OF LOUISIANA
- **Principal Investigator:** Tanika Nicole Kelly
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $166,293
- **Award type:** 5
- **Project period:** 2016-03-10 → 2027-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10927214

## Citation

> US National Institutes of Health, RePORTER application 10927214, Bioinformatics and Biostatistics Core (5P20GM109036-08). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10927214. Licensed CC0.

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